GM-CSF Receptor Beta Recombinant Protein | CSF2RB recombinant protein
Recombinant Human GM-CSF Receptor Beta
Gene Names
CSF2RB; CD131; IL3RB; IL5RB; SMDP5; CDw131
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
GM-CSF Receptor Beta; Recombinant Human GM-CSF Receptor Beta; CSF2RB Human; GM-CSF Receptor Beta Human Recombinant; CSF2RB;Colony Stimulating Factor 2 Receptor; Beta; Low-Affinity (Granulocyte-Macrophage); GM-CSF/IL-3/IL-5 Receptor Common Beta Subunit; CDw131; IL3RB; SMDP5; IL5RB; Interleukin 3 Receptor/Granulocyte-Macrophage Colony Stimulating Factor 3 Receptor; Beta (High Affinity); Colony-Stimulating Factor-2 Receptor; Low-Affinity; GM-CSF/IL-3/IL-5 Receptor Common Beta-Chain; Cytokine Receptor Common Subunit Beta; CD131 Antigen; CD131; CSF2RB recombinant protein
Host
Sf9 Baculovirus Cells
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
CSF2RB protein solution (0.5mg/ml)
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVNEDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEPRDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQNLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATHGQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHSMALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH.
Sequence Length
897
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for CSF2RB recombinant protein
Introduction: GM-CSF Receptor Beta, also known as CSF2RB is a member of the type I cytokine receptor family. CSF2RB is a high affinity receptor for interleukin-3, interleukin-5 as well as granulocyte-macrophage colony-stimulating factor. CSF2RB unique form of receptor assembly applies also to IL-3 and IL-5 receptors, providing a structural basis for understanding their activation mechanism which is essential for the development of therapeutics.
Description: CSF2RB Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 435 amino acids (17-443 a.a) and having a molecular mass of 49.7kDa. (Migrates at 40-57kDa on SDS-PAGE under reducing conditions). CSF2RB is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Description: CSF2RB Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 435 amino acids (17-443 a.a) and having a molecular mass of 49.7kDa. (Migrates at 40-57kDa on SDS-PAGE under reducing conditions). CSF2RB is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for CSF2RB recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
97,976 Da
NCBI Official Full Name
cytokine receptor common subunit beta
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor beta common subunit
NCBI Official Symbol
CSF2RB
NCBI Official Synonym Symbols
CD131; IL3RB; IL5RB; SMDP5; CDw131
NCBI Protein Information
cytokine receptor common subunit beta
UniProt Protein Name
Cytokine receptor common subunit beta
Protein Family
UniProt Gene Name
CSF2RB
UniProt Synonym Gene Names
IL3RB; IL5RB
UniProt Entry Name
IL3RB_HUMAN
Uniprot Description
CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.
Protein type: Membrane protein, integral; Receptor, cytokine
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane
Molecular Function: interleukin-3 receptor activity; interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor activity
Biological Process: cellular protein metabolic process; MAPKKK cascade; respiratory gaseous exchange
Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5
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Product Notes
The CSF2RB csf2rb (Catalog #AAA140976) is a Recombinant Protein produced from Sf9 Baculovirus Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVN EDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEP RDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQ NLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATH GQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHS MALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMW LEH HHHHH.. It is sometimes possible for the material contained within the vial of "GM-CSF Receptor Beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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