Western Blot (WB)
(Western Blot analysis of VASH1 expression in transfected 293T cell line by VASH1 polyclonal antibody. Lane 1: VASH1 transfected lysate (22.44kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human Vasohibin-1 Polyclonal Antibody | anti-VASH1 antibody
Vasohibin-1 (VASH1, VASH, KIAA1036)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of VASH1 expression in transfected 293T cell line by VASH1 polyclonal antibody. Lane 1: VASH1 transfected lysate (22.44kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of VASH1 expression in transfected 293T cell line by VASH1 polyclonal antibody. Lane 1: VASH1 transfected lysate (22.44kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
Uniprot Description
VASH1: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. Belongs to the vasohibin family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: extracellular space; endoplasmic reticulum; apical part of cell; cytoplasm
Biological Process: negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; response to wounding; angiogenesis; cell cycle arrest; negative regulation of blood vessel endothelial cell migration
Research Articles on VASH1
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Product Notes
The VASH1 vash1 (Catalog #AAA6006473) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Vasohibin-1 (VASH1, VASH, KIAA1036) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Vasohibin-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the VASH1 vash1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MPGGKKVAGG GSSGATPTSA AATAPSGVRR LETSEGTSAQ RDEEPEEEGE EDLRDGGVPF FVNRGGLPVD EATWERMWKH VAKIHPDGEK VAQRIRGATD LPKIPIPSVP TFQPSTPVPE RLEAVQRYIR ELQYNHTGTQ FFEIKKSRPL TGLMDLAKEM TKEALPIKCL EAVILGMYPS SPEGEGSGLL WASASCSESE GGVG. It is sometimes possible for the material contained within the vial of "Vasohibin-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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