Linker for activation of T-cells family member 2 (LAT2) Recombinant Protein | LAT2 recombinant protein

Recombinant Human Linker for activation of T-cells family member 2 (LAT2), partial

Cat. Num. AAA1344772

• Gene Names: LAT2; LAB; NTAL; WSCR5; WBSCR5; HSPC046; WBSCR15
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Linker for activation of T-cells family member 2 (LAT2); Recombinant Human Linker for activation of T-cells family member 2 (LAT2); partial; LAT2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-243
• Sequence: MSSGTELLWP GAALLVLLGV AASLCVRCSR PGAKRSEKIY QQRSLREDQQ SFTGSRTYSL VGQAWPGPLA DMAPTRKDKL LQFYPSLEDP ASSRYQNFSK GSRHGSEEAY IDPIAMEYYN WGRFSKPPED DDANSYENVL ICKQKTTETG AQQEGIGGLC RGDLSLSLAL KTGPTSGLCP SASPEEDEES EDYQNSASIH QWRESRKVMG QLQREASPGP VGSPDEEDGE PDYVNGEVAA TEA
• Sequence Length: 243

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for LAT2 recombinant protein

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein.

NCBI and Uniprot Product Information

• NCBI GI #: 14702182
• NCBI GeneID: 7462
• NCBI Accession #: NP_054865.2
• NCBI GenBank Nucleotide #: NM_014146.3
• UniProt Accession #: Q9GZY6; Q9BXX8; Q9NZY9; A6NFK6; A8K209; A8K4F1; D3DXF9
• Molecular Weight: 12,255 Da
• NCBI Official Full Name: linker for activation of T-cells family member 2
• NCBI Official Synonym Full Names: linker for activation of T cells family member 2
• NCBI Official Symbol: LAT2
• NCBI Official Synonym Symbols: LAB; NTAL; WSCR5; WBSCR5; HSPC046; WBSCR15
• NCBI Protein Information: linker for activation of T-cells family member 2
• UniProt Protein Name: Linker for activation of T-cells family member 2
• Protein Family: Linker for activation of T-cells family
• UniProt Gene Name: LAT2
• UniProt Synonym Gene Names: LAB; NTAL; WBS15; WBSCR15; WBSCR5

NCBI Description

This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.