Unconventional myosin-Ic (Myo1c) Recombinant Protein | Myo1c recombinant protein

Recombinant Rat Unconventional myosin-Ic (Myo1c) , partial

• Gene Names: Myo1c; Myr2
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Unconventional myosin-Ic (Myo1c); Recombinant Rat Unconventional myosin-Ic (Myo1c); partial; Myo1c recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,044

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Myo1c recombinant protein

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.

NCBI and Uniprot Product Information

• NCBI GI #: 124107592
• NCBI GeneID: 65261
• NCBI Accession #: NP_075580.2
• NCBI GenBank Nucleotide #: NM_023092.1
• UniProt Accession #: Q63355
• Molecular Weight: 119,811 Da
• NCBI Official Full Name: unconventional myosin-Ic
• NCBI Official Synonym Full Names: myosin 1C
• NCBI Official Symbol: Myo1c
• NCBI Official Synonym Symbols: Myr2
• NCBI Protein Information: unconventional myosin-Ic
• UniProt Protein Name: Unconventional myosin-Ic
• Protein Family: Unconventional myosin
• UniProt Gene Name: Myo1c
• UniProt Synonym Gene Names: Myr2; MMI-beta; MMIb

NCBI Description

novel class-I Myosin found in brain [RGD, Feb 2006]

Uniprot Description

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes ().