Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Myosin-Ic (MYO1C) Standard Curve.)
Human Myosin-Ic (MYO1C) ELISA Kit | MYO1C elisa kit
Human Myosin-Ic (MYO1C) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Myosin-Ic (MYO1C) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Myosin-Ic (MYO1C) Standard Curve.)
Background: MYO1C encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. Myosin-Ic is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of Myosin-Ic also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for MYO1C. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]
Uniprot Description
MYO1C: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Actin-binding; Contractile; Motor; Motility/polarity/chemotaxis; Nucleolus; Lipid-binding
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: myosin I complex; microvillus; mitochondrion; cytoplasmic membrane-bound vesicle; nuclear pore; cytosol; lipid raft; nucleoplasm; ruffle; filamentous actin; membrane; cytoplasm; unconventional myosin complex; stress fiber; nucleolus; basal plasma membrane; plasma membrane; brush border; lateral plasma membrane
Molecular Function: calmodulin binding; protein C-terminus binding; protein binding; Ral GTPase binding; motor activity; actin-dependent ATPase activity; actin binding; ATP binding; receptor binding
Biological Process: mRNA transport; metabolic process; innate immune response; protein targeting to membrane; protein targeting; positive regulation of cell migration
Research Articles on MYO1C
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Product Notes
The Human MYO1C myo1c (Catalog #AAA9715088) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9715088 ELISA Kit recognizes Human MYO1C. It is sometimes possible for the material contained within the vial of "Myosin-Ic (MYO1C), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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