MAGEB2 cdna clone
MAGEB2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
Uniprot Description
MAGE-B2: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp21.3
Molecular Function: protein binding
Research Articles on MAGEB2
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Product Notes
The MAGEB2 mageb2 (Catalog #AAA1278057) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcctcgtg gtcagaagag taagctccgt gcccgtgaga aacgccgcaa ggcccgagat gagacccggg gtctcaatgt tcctcaggtc actgaagcag aggaagaaga ggccccctgc tgttcctctt ctgtttctgg gggtgctgct tcaagctctc ctgctgctgg cattccccag aagcctcaga gagccccaac cactgccgct gctgcagctg cgggtgtttc atccacaaaa tctaaaaaag gtgccaagag ccaccaaggt gagaaaaatg caagttcctc ccaggcctca acatctacta agagcccaag cgaagatcct ctaaccagga agtcagggtc gttggtgcag ttcctgttgt acaagtataa aataaaaaag tccgttacaa agggagaaat gctgaaaatt gttggcaaaa ggttcaggga gcacttccct gagatcctca agaaagcctc tgagggcctc agtgttgtct ttggccttga gctgaataaa gtcaacccca acggccacac ttacaccttc atcgacaagg tagacctcac tgatgaggaa tccctgctca gttcctggga ctttcccagg agaaagcttc tgatgcctct cctgggtgtg atcttcttaa atggcaactc agctactgag gaagagatct gggaattcct gaatatgttg ggagtctatg atggagagga gcactcagtc tttggggaac cctggaagct catcaccaaa gatctggtgc aggaaaaata tctggagtac aagcaggtgc ccagcagtga tcccccacgc tttcaattcc tgtggggtcc gagagcctat gctgaaacca gcaagatgaa agtcctggag tttttggcca aggtaaatgg taccaccccc tgtgccttcc caacccatta cgaagaagct ttgaaagatg aagagaaagc cggagtctga. It is sometimes possible for the material contained within the vial of "MAGEB2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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