PSMD14 cdna clone
PSMD14 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2. [provided by RefSeq, Feb 2012]
Uniprot Description
PSMD14: a component of the 26S proteasome. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
Protein type: Protease; EC 3.4.19.-; Proteasome complex
Chromosomal Location of Human Ortholog: 2q24.2
Cellular Component: cytosol; nucleoplasm; nucleus; proteasome complex
Molecular Function: metallopeptidase activity; protein binding
Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; double-strand break repair via homologous recombination; double-strand break repair via nonhomologous end joining; MAPKKK cascade; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; ubiquitin-dependent protein catabolic process; Wnt receptor signaling pathway, planar cell polarity pathway
Research Articles on PSMD14
Similar Products
Product Notes
The PSMD14 psmd14 (Catalog #AAA1276133) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggacagac ttcttagact tggaggaggt atgcctggac tgggccaggg gccacctaca gatgctcctg cagtggacac agcagaacaa gtctatatct cttccctggc actgttaaaa atgttaaaac atggccgtgc tggagttcca atggaagtta tgggtttgat gcttggagaa tttgttgatg attataccgt cagagtgatt gatgtgtttg ctatgccaca gtcaggaaca ggtgtcagtg tggaggcagt tgatccagtg ttccaagcta aaatgttgga tatgttgaag cagacaggaa ggccggagat ggttgttggt tggtatcaca gtcaccctgg ctttggttgt tggctttctg gtgtggatat caacactcag cagagctttg aagccttgtc ggagagagct gtggcagtgg ttgtggatcc cattcagagt gtaaaaggaa aggttgttat tgatgccttc agattgatca atgctaatat gatggtctta ggacatgaac caagacaaac aacttcgaat ctgggtcact taaacaagcc atctatccag gcattaattc atggactaaa cagacattat tactccatta ctattaacta tcggaaaaat gaactggaac agaagatgtt gctaaatttg cataagaaga gttggatgga aggtttgaca cttcaggact acagtgaaca ttgtaaacac aatgaatcag tggtaaagga gatgttggaa ttagccaaga attacaataa ggctgtagaa gaagaagata agatgacacc tgaacagctg gcaataaaga atgttggcaa gcaggacccc aaacgtcatt tggaggaaca tgtggatgta cttatgacct caaatattgt ccagtgttta gcagctatgt tggatactgt cgtatttaaa taa. It is sometimes possible for the material contained within the vial of "PSMD14, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
