TGFBRAP1 cdna clone
TGFBRAP1 cDNA Clone
Gene Names
TGFBRAP1; VPS3; TRAP1; TRAP-1
Synonyms
TGFBRAP1; TGFBRAP1 cDNA Clone; TGFBRAP1 cdna clone
Sequence
atgatgagcatcaaagcctttacgcttgtctctgctgtggagcgggagctgctgatgggcgacaaggagcgcgtcaacatagagtgcgtggagtgctgcggcagggacctctacgtgggcaccaacgactgcttcgtctaccacttcctgttggaggagaggccagtgcctgctgggccagccacgttcactgccaccaaacagctgcagagacacttgggcttcaagaagcccgtgaacgagctgcgcgcggcctcagcactcaacaggctgctggtgctgtgtgacaactccatcagcctggtcaacatgctgaacctcgagccagtgccttcgggggcccgcatcaagggggcagccacgtttgcactgaacgagaaccctgtgagtggggaccccttctgtgtagaagtttgcatcatctctgtcaaacgcagaaccatccagatgtttctggtgtacgaggaccgggtgcagatcgtcaaggaggtgtcgactgccgagcagcccctcgctgtggctgtggacggccacttcctgtgtctggctctgaccactcagtacatcatccacaattacagcacaggcgtctcccaggacctttttccctactgcagtgaggagaggccgccgatcgtcaagaggatagggagacaggagttcctgctggcgggccccggagggctgggcatgtttgccacagtcgcagggatatcccagcgtgcccccgtgcactggtcggagaatgtgattggggcggctgtgtcctttccatacgtcatagcgctcgatgacgaattcatcacagtccacagcatgttggatcagcaacagaagcagacgctgccctttaaggagggccatatcctacaggactttgaaggaagagtgatcgttgccacaagtaaaggagtttacatcttggttccattacctttggaaaaacaaatacaggatcttctagcaagccgcagagtagaagaggctttggttttagcaaaaggagcccggaggaacattccaaaggaaaaatttcaggtaatgtacagaaggattctgcagcaggcgggatttatacagtttgcacaacttcagttcctggaagctaaagagctcttcagaagcggccagcttgatgtccgggagctgatctctctctaccccttcctgttgcccacctcctcctccttcacccggtcccaccctcctcttcatgagtacgcagacctgaaccagctgacccagggggaccaggagaagatggccaagtgcaaacgcttcctcatgagctacctgaacgaggtccgcagcacagaggtagcaaatggctacaaggaggacatcgacacagccttgctcaaactgtatgcagaggctgaccacgacagcctgctggacctcctggtcactgagaacttctgtcttctgacggacagtgctgcctggctagagaagcacaaaaagtattttgcacttggactgctctatcattataataaccaagatgctgctgcagttcagttgtgggtgaacattgtgaatggcgatgtccaggactccacacgctcagacctgtatgaatacatcgtggattttcttacctactgcttagacgaggaactagtgtgggcctatgctgattgggtcctgcagaaaagtgaagaggtcggagttcaggttttcaccaagagacctttggatgaacagcagaagaacagttttaatccagacgacattatcaattgccttaaaaaataccctaaagcccttgtgaagtatctggaacatcttgtgatagacaagagactgcagaaagaagagtatcacacccacttagctgtgctgtacctggaagaggtgctgctgcagagggcctccgccagtggcaagggtgcagaggccaccgagacgcaggccaagctgcggcggctgctccagaaatctgatttataccgagtccactttcttctcgagaggctgcagggagctggcctgcccatggagagcgccatcctgcacgggaagctgggcgagcatgagaaggcgctgcatatcctggtgcacgagctgcaggactttgcagcggccgaggactactgcctgtggtgctccgagggccgagacccaccccaccgccagcaactctttcacacgctgctggccatctacctgcatgctggccccactgcccacgagctggccgtggctgccgtggacctgctgaaccgccacgccaccgaatttgatgcagcccaggtgctgcagatgctgcctgacacctggtcagtgcagctcctctgcccattcctgatgggggccatgagggacagcatccatgccaggaggaccatgcaggtggctctcggcctggccaggtccgaaaacttaatctacacctacgataagatgaagttgaaaggaagctcaatccaactctcagacaaaaagctttgtcagatatgccaaaatcccttttgtgagcctgtgtttgttagatacccaaatggtggtcttgtgcacacccactgtgccgccagcagacacacaaaccccagctcatccagtcctggcactcggacttga
Sequence Length
2583
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
97,158 Da
NCBI Official Full Name
Homo sapiens transforming growth factor, beta receptor associated protein 1, mRNA
NCBI Official Synonym Full Names
transforming growth factor beta receptor associated protein 1
NCBI Official Symbol
TGFBRAP1
NCBI Official Synonym Symbols
VPS3; TRAP1; TRAP-1
NCBI Protein Information
transforming growth factor-beta receptor-associated protein 1
UniProt Protein Name
Transforming growth factor-beta receptor-associated protein 1
Protein Family
UniProt Gene Name
TGFBRAP1
UniProt Synonym Gene Names
TGF-beta receptor-associated protein 1; TRAP-1; TRAP1
UniProt Entry Name
TGFA1_HUMAN
NCBI Description
This gene encodes a protein that binds to transforming growth factor-beta (TGF-beta) receptors and plays a role in TGF-beta signaling. The encoded protein acts as a chaprone in signaling downstream of TGF-beta. It is involved in signal-dependent association with SMAD4. The protein is also a component of mammalian CORVET, a multisubunit tethering protein complex that is involved in fusion of early endosomes. [provided by RefSeq, Jun 2016]
Uniprot Description
TGFBRAP1: Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Belongs to the TRAP1 family.
Chromosomal Location of Human Ortholog: 2q12.1
Cellular Component: early endosome; membrane
Molecular Function: protein binding; SMAD binding; transforming growth factor beta receptor binding
Biological Process: endosomal vesicle fusion; endosome to lysosome transport; regulation of transcription, DNA-dependent; signal transduction; transforming growth factor beta receptor signaling pathway
Research Articles on TGFBRAP1
Similar Products
Product Notes
The TGFBRAP1 tgfbrap1 (Catalog #AAA1271588) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgatgagca tcaaagcctt tacgcttgtc tctgctgtgg agcgggagct gctgatgggc gacaaggagc gcgtcaacat agagtgcgtg gagtgctgcg gcagggacct ctacgtgggc accaacgact gcttcgtcta ccacttcctg ttggaggaga ggccagtgcc tgctgggcca gccacgttca ctgccaccaa acagctgcag agacacttgg gcttcaagaa gcccgtgaac gagctgcgcg cggcctcagc actcaacagg ctgctggtgc tgtgtgacaa ctccatcagc ctggtcaaca tgctgaacct cgagccagtg ccttcggggg cccgcatcaa gggggcagcc acgtttgcac tgaacgagaa ccctgtgagt ggggacccct tctgtgtaga agtttgcatc atctctgtca aacgcagaac catccagatg tttctggtgt acgaggaccg ggtgcagatc gtcaaggagg tgtcgactgc cgagcagccc ctcgctgtgg ctgtggacgg ccacttcctg tgtctggctc tgaccactca gtacatcatc cacaattaca gcacaggcgt ctcccaggac ctttttccct actgcagtga ggagaggccg ccgatcgtca agaggatagg gagacaggag ttcctgctgg cgggccccgg agggctgggc atgtttgcca cagtcgcagg gatatcccag cgtgcccccg tgcactggtc ggagaatgtg attggggcgg ctgtgtcctt tccatacgtc atagcgctcg atgacgaatt catcacagtc cacagcatgt tggatcagca acagaagcag acgctgccct ttaaggaggg ccatatccta caggactttg aaggaagagt gatcgttgcc acaagtaaag gagtttacat cttggttcca ttacctttgg aaaaacaaat acaggatctt ctagcaagcc gcagagtaga agaggctttg gttttagcaa aaggagcccg gaggaacatt ccaaaggaaa aatttcaggt aatgtacaga aggattctgc agcaggcggg atttatacag tttgcacaac ttcagttcct ggaagctaaa gagctcttca gaagcggcca gcttgatgtc cgggagctga tctctctcta ccccttcctg ttgcccacct cctcctcctt cacccggtcc caccctcctc ttcatgagta cgcagacctg aaccagctga cccaggggga ccaggagaag atggccaagt gcaaacgctt cctcatgagc tacctgaacg aggtccgcag cacagaggta gcaaatggct acaaggagga catcgacaca gccttgctca aactgtatgc agaggctgac cacgacagcc tgctggacct cctggtcact gagaacttct gtcttctgac ggacagtgct gcctggctag agaagcacaa aaagtatttt gcacttggac tgctctatca ttataataac caagatgctg ctgcagttca gttgtgggtg aacattgtga atggcgatgt ccaggactcc acacgctcag acctgtatga atacatcgtg gattttctta cctactgctt agacgaggaa ctagtgtggg cctatgctga ttgggtcctg cagaaaagtg aagaggtcgg agttcaggtt ttcaccaaga gacctttgga tgaacagcag aagaacagtt ttaatccaga cgacattatc aattgcctta aaaaataccc taaagccctt gtgaagtatc tggaacatct tgtgatagac aagagactgc agaaagaaga gtatcacacc cacttagctg tgctgtacct ggaagaggtg ctgctgcaga gggcctccgc cagtggcaag ggtgcagagg ccaccgagac gcaggccaag ctgcggcggc tgctccagaa atctgattta taccgagtcc actttcttct cgagaggctg cagggagctg gcctgcccat ggagagcgcc atcctgcacg ggaagctggg cgagcatgag aaggcgctgc atatcctggt gcacgagctg caggactttg cagcggccga ggactactgc ctgtggtgct ccgagggccg agacccaccc caccgccagc aactctttca cacgctgctg gccatctacc tgcatgctgg ccccactgcc cacgagctgg ccgtggctgc cgtggacctg ctgaaccgcc acgccaccga atttgatgca gcccaggtgc tgcagatgct gcctgacacc tggtcagtgc agctcctctg cccattcctg atgggggcca tgagggacag catccatgcc aggaggacca tgcaggtggc tctcggcctg gccaggtccg aaaacttaat ctacacctac gataagatga agttgaaagg aagctcaatc caactctcag acaaaaagct ttgtcagata tgccaaaatc ccttttgtga gcctgtgttt gttagatacc caaatggtgg tcttgtgcac acccactgtg ccgccagcag acacacaaac cccagctcat ccagtcctgg cactcggact tga. It is sometimes possible for the material contained within the vial of "TGFBRAP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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