Western Blot (WB)
(Western blot analysis of TMOD2 using K562 whole cell lysates)
Rabbit anti-Human, Rat TMOD2 Polyclonal Antibody | anti-TMOD2 antibody
TMOD2 Antibody
Gene Names
TMOD2; NTMOD; N-TMOD
Reactivity
Human, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TMOD2; Polyclonal Antibody; TMOD2 Antibody; Tropomodulin 2; MGC39481; N Tmod; Neuronal tropomodulin; NTMOD; tropomodulin 2 (neuronal); tropomodulin 2 neuronal; anti-TMOD2 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TMOD2 antibody detects endogenous levels of total TMOD2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
315
Applicable Applications for anti-TMOD2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-3000
IHC: 1:200
IHC: 1:200
Immunogen
A synthesized peptide derived from human TMOD2
Subcellular Location
Cytoskeleton
Tissue Specificity
Neuronal-tissue specific.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (89%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of TMOD2 using K562 whole cell lysates)
Western Blot (WB)
(Western blot analysis of TMOD2 using K562 whole cell lysates)
Immunohistochemistry (IHC)
(MBS9608688 at 1/100 staining Rat colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Immunohistochemistry (IHC)
(MBS9608688 at 1/100 staining Rat colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Related Product Information for anti-TMOD2 antibody
Function: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
Subunit Structure: Binds to the N-terminus of tropomyosin and to actin.
Similarity: Belongs to the tropomodulin family.
Subunit Structure: Binds to the N-terminus of tropomyosin and to actin.
Similarity: Belongs to the tropomodulin family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 40 kDa
Predicted: 40 kDa
Predicted: 40 kDa
NCBI Official Full Name
tropomodulin-2 isoform b
NCBI Official Synonym Full Names
tropomodulin 2
NCBI Official Symbol
TMOD2
NCBI Official Synonym Symbols
NTMOD; N-TMOD
NCBI Protein Information
tropomodulin-2
UniProt Protein Name
Tropomodulin-2
Protein Family
UniProt Gene Name
TMOD2
UniProt Synonym Gene Names
NTMOD; N-Tmod
NCBI Description
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008]
Uniprot Description
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton ().
Research Articles on TMOD2
Similar Products
Product Notes
The TMOD2 tmod2 (Catalog #AAA9608688) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMOD2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMOD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-3000 IHC: 1:200. Researchers should empirically determine the suitability of the TMOD2 tmod2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMOD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
