SPATA13 cdna clone
SPATA13 cDNA Clone
Gene Names
SPATA13; ASEF2; ARHGEF29
Synonyms
SPATA13; SPATA13 cDNA Clone; SPATA13 cdna clone
Sequence
ATGACTTCTGCCAGCCCTGAAGACCAGAATGCTCCAGTGGGCTGCCCCAAAGGAGCCCGGAGAAGGCGCCCCATTTCCGTGATAGGTGGGGTCAGCTTGTATGGGACCAACCAGACGGAGGAACTGGACAATCTTCTGACCCAACCGGCTTCCAGGCCGCCCATGCCTGCTCACCAGGTGCCACCCTACAAGGCTGTGTCGGCCCGGTTCCGGCCCTTCACATTCTCCCAGAGCACCCCCATTGGGTTGGACCGTGTGGGACGCCGGCGGCAGATGAGAGCATCCAACGTTTCTTCAGATGGAGGTACTGAGCCCTCTGCCTTAGTGGATGACAACGGTAGTGAGGAGGACTTCAGCTATGAAGACCTCTGCCAGGCCAGCCCTCGGTACCTGCAGCCCGGCGGGGAGCAGCTGGCCATCAATGAGCTGATCAGTGATGGCAACGTGGTCTGCGCAGAAGCCCTGTGGGACCATGTGACCATGGATGACCAGGAACTGGGCTTCAAAGCCGGGGATGTCATCCAGGTTCTGGAAGCCTCCAACAAGGACTGGTGGTGGGGCCGCAGTGAAGATAAGGAAGCCTGGTTCCCCGCGAGCTTCGTCAGATTGCGAGTGAATCAGGAAGAGCTGTCGGAAAACTCCAGCAGCACCCCCAGTGAGGAGCAGGACGAGGAGGCCAGCCAGAGCCGCCACAGACACTGTGAGAACAAGCAGCAGATGCGGACCAACGTCATCCGGGAGATCATGGACACCGAGCGGGTGTACATCAAACACCTCAGGGACATCTGTGAGGGCTATATCCGACAGTGCCGCAAGCACACAGGAATGTTCACCGTTGCGCAGCTAGCCACTATTTTTGGAAACATTGAAGATATTTACAAATTCCAAAGAAAGTTTCTGAAAGACCTTGAGAAACAGTACAACAAAGAGGAACCTCACTTAAGTGAAATAGGATCTTGCTTTCTTCAAAATCAAGAGGGCTTTGCCATCTATTCCGAGTACTGCAACAACCACCCGGGCGCCTGCCTGGAGCTCGCCAACCTCATGAAGCAGGGCAAGTACAGACATTTCTTTGAAGCCTGCCGCCTGCTGCAGCAGATGATTGACATCGCCATCGACGGGTTCCTGCTCACACCAGTGCAGAAGATCTGCAAATACCCGCTGCAGCTGGCCGAGCTGCTCAAGTATACCACACAGGAACACGGTGATTACAGCAACATAAAGGCAGCATATGAGGCCATGAAGAATGTGGCCTGTCTGATCAACGAGCGCAAGCGCAAGCTGGAGAGCATCGACAAGATAGCTCGCTGGCAGGTGTCTATCGTGGGCTGGGAGGGACTGGATATCTTAGACCGAAGCTCAGAATTGATTCATTCTGGGGAGCTGACCAAAATCACTAAGCAAGGCAAAAGCCAGCAGCGGACGTTCTTCCTGTTTGACCACCAGCTGGTGTCCTGCAAGAAGGACCTGCTGCGCAGGGACATGCTGTACTACAAGGGCCGGCTGGACATGGATGAGATGGAGCTTGTGGACCTGGGGGATGGGCGCGACAAGGACTGCAACCTCAGCGTGAAAAATGCCTTCAAGCTCGTCAGTAGGACCACAGACGAGGTTTATTTGTTTTGTGCCAAAAAACAAGAAGACAAGGCGAGGTGGCTGCAGGCCTGTGCAGATGAAAGGAGGCGGGTGCAAGAGGACAAGGAGATGGGAATGGAAATTTCAGAAAACCAGAAGAAACTTGCCATGTTAAATGCTCAAAAGGCAGGACATGGAAAGTCAAAAGGCTACAACAGGTGCCCTGTGGCCCCACCGCACCAGGGCCTGCACCCCATCCACCAGCGCCACATCACTATGCCCACAAGCGTCCCCCAGCAGCAGGTCTTTGGCCTGGCGGAACCCAAGAGGAAGTCCTCGCTCTTCTGGCACACCTTCAACAGGCTCACCCCCTTCCGGAAATGA
Sequence Length
1959
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
141,436 Da
NCBI Official Full Name
Homo sapiens spermatogenesis associated 13, mRNA
NCBI Official Synonym Full Names
spermatogenesis associated 13
NCBI Official Symbol
SPATA13
NCBI Official Synonym Symbols
ASEF2; ARHGEF29
NCBI Protein Information
spermatogenesis-associated protein 13
UniProt Protein Name
Spermatogenesis-associated protein 13
Protein Family
UniProt Gene Name
SPATA13
UniProt Synonym Gene Names
Asef2
UniProt Entry Name
SPT13_HUMAN
Uniprot Description
SPATA13 iso6: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up- regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. Interacts (via ABR and SH3 domain) with APC. The binding of APC enhances its GEF activity by relieving it from an autoinhibitory conformation, in which the ABR and SH3 domains are associated with the C-terminal tail. Interacts (via C-terminal tail) with PPP1R9B (via C-terminus). Interacts with RAC1. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rac/Rho
Chromosomal Location of Human Ortholog: 13q12.12
Cellular Component: cytoplasm; filopodium; lamellipodium; nucleoplasm
Molecular Function: guanyl-nucleotide exchange factor activity; protein binding; Rac guanyl-nucleotide exchange factor activity
Biological Process: cell migration; filopodium formation; lamellipodium biogenesis; regulation of cell migration
Research Articles on SPATA13
Similar Products
Product Notes
The SPATA13 spata13 (Catalog #AAA1268320) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGACTTCTG CCAGCCCTGA AGACCAGAAT GCTCCAGTGG GCTGCCCCAA AGGAGCCCGG AGAAGGCGCC CCATTTCCGT GATAGGTGGG GTCAGCTTGT ATGGGACCAA CCAGACGGAG GAACTGGACA ATCTTCTGAC CCAACCGGCT TCCAGGCCGC CCATGCCTGC TCACCAGGTG CCACCCTACA AGGCTGTGTC GGCCCGGTTC CGGCCCTTCA CATTCTCCCA GAGCACCCCC ATTGGGTTGG ACCGTGTGGG ACGCCGGCGG CAGATGAGAG CATCCAACGT TTCTTCAGAT GGAGGTACTG AGCCCTCTGC CTTAGTGGAT GACAACGGTA GTGAGGAGGA CTTCAGCTAT GAAGACCTCT GCCAGGCCAG CCCTCGGTAC CTGCAGCCCG GCGGGGAGCA GCTGGCCATC AATGAGCTGA TCAGTGATGG CAACGTGGTC TGCGCAGAAG CCCTGTGGGA CCATGTGACC ATGGATGACC AGGAACTGGG CTTCAAAGCC GGGGATGTCA TCCAGGTTCT GGAAGCCTCC AACAAGGACT GGTGGTGGGG CCGCAGTGAA GATAAGGAAG CCTGGTTCCC CGCGAGCTTC GTCAGATTGC GAGTGAATCA GGAAGAGCTG TCGGAAAACT CCAGCAGCAC CCCCAGTGAG GAGCAGGACG AGGAGGCCAG CCAGAGCCGC CACAGACACT GTGAGAACAA GCAGCAGATG CGGACCAACG TCATCCGGGA GATCATGGAC ACCGAGCGGG TGTACATCAA ACACCTCAGG GACATCTGTG AGGGCTATAT CCGACAGTGC CGCAAGCACA CAGGAATGTT CACCGTTGCG CAGCTAGCCA CTATTTTTGG AAACATTGAA GATATTTACA AATTCCAAAG AAAGTTTCTG AAAGACCTTG AGAAACAGTA CAACAAAGAG GAACCTCACT TAAGTGAAAT AGGATCTTGC TTTCTTCAAA ATCAAGAGGG CTTTGCCATC TATTCCGAGT ACTGCAACAA CCACCCGGGC GCCTGCCTGG AGCTCGCCAA CCTCATGAAG CAGGGCAAGT ACAGACATTT CTTTGAAGCC TGCCGCCTGC TGCAGCAGAT GATTGACATC GCCATCGACG GGTTCCTGCT CACACCAGTG CAGAAGATCT GCAAATACCC GCTGCAGCTG GCCGAGCTGC TCAAGTATAC CACACAGGAA CACGGTGATT ACAGCAACAT AAAGGCAGCA TATGAGGCCA TGAAGAATGT GGCCTGTCTG ATCAACGAGC GCAAGCGCAA GCTGGAGAGC ATCGACAAGA TAGCTCGCTG GCAGGTGTCT ATCGTGGGCT GGGAGGGACT GGATATCTTA GACCGAAGCT CAGAATTGAT TCATTCTGGG GAGCTGACCA AAATCACTAA GCAAGGCAAA AGCCAGCAGC GGACGTTCTT CCTGTTTGAC CACCAGCTGG TGTCCTGCAA GAAGGACCTG CTGCGCAGGG ACATGCTGTA CTACAAGGGC CGGCTGGACA TGGATGAGAT GGAGCTTGTG GACCTGGGGG ATGGGCGCGA CAAGGACTGC AACCTCAGCG TGAAAAATGC CTTCAAGCTC GTCAGTAGGA CCACAGACGA GGTTTATTTG TTTTGTGCCA AAAAACAAGA AGACAAGGCG AGGTGGCTGC AGGCCTGTGC AGATGAAAGG AGGCGGGTGC AAGAGGACAA GGAGATGGGA ATGGAAATTT CAGAAAACCA GAAGAAACTT GCCATGTTAA ATGCTCAAAA GGCAGGACAT GGAAAGTCAA AAGGCTACAA CAGGTGCCCT GTGGCCCCAC CGCACCAGGG CCTGCACCCC ATCCACCAGC GCCACATCAC TATGCCCACA AGCGTCCCCC AGCAGCAGGT CTTTGGCCTG GCGGAACCCA AGAGGAAGTC CTCGCTCTTC TGGCACACCT TCAACAGGCT CACCCCCTTC CGGAAATGA. It is sometimes possible for the material contained within the vial of "SPATA13, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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