Western Blot (WB)
(Western Blot analysis of extracts of various cells, using CAPRIN1 antibody.)
Rabbit CAPRIN1 Polyclonal Antibody | anti-CAPRIN1 antibody
CAPRIN1 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CAPRIN1; Polyclonal Antibody; CAPRIN1 Polyclonal Antibody; M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI; anti-CAPRIN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CAPRIN1 polyclonal antibody detects endogenous levels of CAPRIN1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
709
Applicable Applications for anti-CAPRIN1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
Recombinant protein of human CAPRIN1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using CAPRIN1 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cells, using CAPRIN1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded mouse brain using CAPRIN1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded mouse brain using CAPRIN1 antibody.)
Related Product Information for anti-CAPRIN1 antibody
Caprin1, also known as GPIAP1, GPIP137 or M11S1, is a 709 amino acid protein that localizes to the cytoplasm, as well as to the cytosol and the cell projection and belongs to the caprin family. Expressed ubiquitously as multiple alternatively spliced isoforms, Caprin1 is thought to regulate the transport and subsequent translation of mRNAs that encode proteins which are involved in synaptic plasticity and cellular proliferation. Caprin1 interacts directly with several proteins, including G3BP1, CaMKIIalpha and BDNF and may function in homomultimeric structures. The gene encoding Caprin1 maps to human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
NCBI and Uniprot Product Information
Uniprot Description
CAPRIN1: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Belongs to the caprin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Cell surface
Chromosomal Location of Human Ortholog: 11p13
Cellular Component: membrane; stress granule; integral to plasma membrane; cytoplasm; dendrite; cytosol
Molecular Function: RNA binding
Biological Process: negative regulation of translation; positive regulation of dendrite morphogenesis
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Product Notes
The CAPRIN1 caprin1 (Catalog #AAA3008944) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPRIN1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAPRIN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CAPRIN1 caprin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAPRIN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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