Selection and upkeep of intraepithelial T-cells protein 1 (Skint1) Recombinant Protein | Skint1 recombinant protein

Recombinant Mouse Selection and upkeep of intraepithelial T-cells protein 1 (Skint1)

• Gene Names: Skint1; Skint-1; OTTMUSG00000008542
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Selection and upkeep of intraepithelial T-cells protein 1 (Skint1); Recombinant Mouse Selection and upkeep of intraepithelial T-cells protein 1 (Skint1); Recombinant Selection and upkeep of intraepithelial T-cells protein 1 (Skint1); Selection and upkeep of intraepithelial T-cells protein 1; Skint-1; Immunoglobulin-like and transmembrane domain-containing protein expressed in skin and thymus protein 1; Skint1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 24-364
• Sequence: SSEPFIVNGLEGPVLASLGGNLELSCQLSPPQQAQHMEIRWFRNLYTEPVHLYRDGKDMFGEIISKYVERTELLKDGIGEGKVTLRIFNVTVDDDGSYHCVFKDGDFYEEHITEVKITAINLQVQIHVHPPNTKGVIVECHSGGWFPRPLMQWRDRRGEVIPAASKSHSQGRDKLFNMKISLLISESFFQKVICCLQNPLTGQEERTSVILSDAFFSWNRIWKMILGIILSMMVVSIFVFSCLLHHEHKVCKWKWDAPWIKGLLIMTSSMVTVVLVMVYLHMKQRVPVSDVHFELDTLWVEDISVILCSLMVPATMLVSYTYFRLKDWCQHNHAQRVFTSN
• Sequence Length: 364

• Species: Mus musculus (Mouse)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 156627588
• NCBI GeneID: 639781
• NCBI Accession #: NP_001096132.1
• NCBI GenBank Nucleotide #: NM_001102662.1
• UniProt Accession #: A7TZE6; A7TZE7; A7XUW2; A7XUW8; A7XUX1; A9XK90
• Molecular Weight: 41,792 Da
• NCBI Official Full Name: selection and upkeep of intraepithelial T-cells protein 1
• NCBI Official Synonym Full Names: selection and upkeep of intraepithelial T cells 1
• NCBI Official Symbol: Skint1
• NCBI Official Synonym Symbols: Skint-1; OTTMUSG00000008542
• NCBI Protein Information: selection and upkeep of intraepithelial T-cells protein 1; skint 1; Immunoglobulin-like and transmembrane domain-containing protein expressed in skin and thymus protein 1
• UniProt Protein Name: Selection and upkeep of intraepithelial T-cells protein 1
• Protein Family: Selection and upkeep of intraepithelial T-cells protein
• UniProt Gene Name: Skint1
• UniProt Synonym Gene Names: Skint-1
• UniProt Entry Name: SKIT1_MOUSE

Uniprot Description

Function: May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus. Plays a central role in mediating key epithelial-immune interactions by being involved in the selection of Vgamma5+Vdelta1+ T-cells, which constitute 90% of epidermal gammadelta T-cells. Ref.1

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Tissue specificity: Expressed in skin and thymus. Ref.1

Polymorphism: The strain FVB/NTac displays a selective deficiency for epidermal Vgamma5+Vdelta1+ T-cells due to a mutation that creates premature codon stop at position 324.

Miscellaneous: Encoded by one of the 11 copies of Skint genes clustered in the D1 region of the chromosome 4.The human orthologous protein family seems not to exist.

Sequence similarities: Belongs to the SKINT family.Contains 1 Ig-like C1-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.