E3 ubiquitin-protein ligase ICP0 (RL2) Recombinant Protein | RL2 recombinant protein
Recombinant Human herpesvirus 2 E3 ubiquitin-protein ligase ICP0 (RL2), partial
NCBI and Uniprot Product Information
Uniprot Description
Evades nuclear antiviral defenses triggered by dsDNA viruses. Acts during the initial stages of lytic infection and the reactivation of latent viral genome. Prevents the antiviral effect of nuclear bodies by degrading host PML and SP100. Prevents antiviral response to viral DNA induced by IFI16 by degrading it. Additionally, inhibits host IRF3 nuclear signaling to prevent interferon production by the infected cells.
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Product Notes
The RL2 rl2 (Catalog #AAA1100408) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 389-684, Partial. The amino acid sequence is listed below: SAQVSSGPGG GGLPQSSGRA ARPRAAVAPR VRSPPRAAAA PVVSASADAA GPAPPAVPVD AHRAPRSRMT QAQTDTQAQS LGRAGATDAR GSGGPGAEGG PGVPRGTNTP GAAPHAAEGA AARPRKRRGS DSGPAASSSA SSSAAPRSPL APQGVGAKRA APRRAPDSDS GDRGHGPLAP ASAGAAPPSA SPSSQAAVAA ASSSSASSSS ASSSSASSSS ASSSSASSSS ASSSSASSSA GGAGGSVASA SGAGERRETS LGPRAAAPRG PRKCARKTRH AEGGPEPGAR DPAPGL . It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase ICP0 (RL2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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