Chemical Structure
5-fluoro 203, Inhibitor | 5-fluoro203, inhibitor
5-fluoro 203
Purity
0.9802
Synonyms
5-fluoro 203; 5F-203; NSC-703786; 5-fluoro203; inhibitor
Purity/Purification
0.9802
Form/Format
Solid
Solubility
DMSO: 10mM
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
CC1=C(C=CC(=C1)C2=NC3=C(S2)C=CC(=C3)F)N
Formula
C14H11FN2S
CAS Number
260443-89-8
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).
Chemical Structure
Chemical Structure
Related Product Information for 5-fluoro203, inhibitor
5-fluoro 203 is a cytotoxic molecule leading to cell death by forming DNA adducts.5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1.5-fluoro 203 treatment of cells also leads to elevation of reactive oxygen species and activation of p38,JNK and ERK.
References
Mclean L S, Watkins C N, Campbell P, et al. Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells[J]. Chemical Research in Toxicology, 2015, 28(5):855-71.
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Product Notes
The 5-fluoro203 (Catalog #AAA5764812) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "5-fluoro 203, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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