Source: Prokaryotic expression
LFL TKFIHTLESQ RTFSARDRAY VASLLTVALH GKLEYFTDIL RTLLSDLVAQ YVAKNPKLML RRTETVVEKL LTNWMSICLY TFVRDSVGEP LYMLFRGIKH QVDKGPVDSV TGKAKYTLND NRLLREDVEY RPLTLNALLA VGPGAGEAQC VPVKVLDCDT ISQAKEKMLD QLYKGVPLAQ RPDSCTLDVE WRSGVAGHLI LSDEDVTSEL QGLWRRLNTL QHYKVPDGAT VALVPCLTKHILRENQDYV
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
Uniprot Description
PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Motility/polarity/chemotaxis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: integral to plasma membrane; plasma membrane; extracellular region; intracellular
Molecular Function: protein binding; transmembrane receptor activity; semaphorin receptor activity; GTPase activating protein binding; receptor activity; semaphorin receptor binding
Biological Process: positive regulation of phosphoinositide 3-kinase cascade; axon guidance; regulation of cell shape; cell migration; positive regulation of axonogenesis; negative regulation of osteoblast proliferation; negative regulation of cell adhesion; signal transduction; neurite morphogenesis; regulation of cytoskeleton organization and biogenesis
Research Articles on PLXNB1
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Product Notes
The PLXNB1 plxnb1 (Catalog #AAA2029252) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Plexin B1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the PLXNB1 plxnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.LFL TKFIHTLESQ RTFSARDRAY VASLLTVALH GKLEYFTDIL RTLLSDLVAQ YVAKNPKLML RRTETVVEKL LTNWMSICLY TFVRDSVGEP LYMLFRGIKH QVDKGPVDSV TGKAKYTLND NRLLREDVEY RPLTLNALLA VGPGAGEAQC VPVKVLDCDT ISQAKEKMLD QLYKGVPLAQ RPDSCTLDVE WRSGVAGHLI LSDEDVTSEL QGLWRRLNTL QHYKVPDGAT VALVPCLTKH ILRENQDYV. It is sometimes possible for the material contained within the vial of "Plexin B1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.
Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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