Mouse Zinc Transporter 6 (SLC30A6) ELISA Kit | ZNT6 elisa kit
Mouse Zinc Transporter 6 (SLC30A6) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Background: Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc. The deduced mouse and human proteins contain 460 amino acids and share 92% identity. Mouse Znt6 has 6 transmembrane domains, a loop between transmembrane domains 4 and 5, and cytoplasmic N and C termini. In contrast to other Znt proteins, the loop region of Znt6 lacks multiple histidines. Normal rat kidney cells expressed Znt6 in a perinuclear location and in a punctate/tubular pattern throughout the cytoplasm and under the plasma membrane. Disruption of the Golgi compartment also disrupted Znt6 localization.
NCBI and Uniprot Product Information
Uniprot Description
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.
Research Articles on ZNT6
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Product Notes
The Mouse ZNT6 slc30a6 (Catalog #AAA9717032) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717032 ELISA Kit recognizes Mouse ZNT6. It is sometimes possible for the material contained within the vial of "Zinc Transporter 6 (SLC30A6), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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