Mouse zinc finger CCCH-type containing 12A ELISA Kit | ZC3H12A elisa kit
Mouse Ribonuclease ZC3H12A, ZC3H12A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
MCPIP1: Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA. Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. Belongs to the ZC3H12 family.
Protein type: EC 3.1.-.-; Hydrolase
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; nuclease activity; hydrolase activity; endonuclease activity; metal ion binding; T/G mismatch-specific endonuclease activity; phosphoric ester hydrolase activity
Biological Process: apoptosis; inhibition of NF-kappaB transcription factor; multicellular organismal development; negative regulation of nitric oxide biosynthetic process; negative regulation of interleukin-6 production; positive regulation of fat cell differentiation; angiogenesis; negative regulation of tumor necrosis factor production; cell differentiation; positive regulation of autophagy
Research Articles on ZC3H12A
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Product Notes
The Mouse ZC3H12A zc3h12a (Catalog #AAA9343341) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343341 ELISA Kit recognizes Mouse ZC3H12A. It is sometimes possible for the material contained within the vial of "zinc finger CCCH-type containing 12A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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