Rat X-ray repair complementing defective repair in Chinese hamster cells 1 ELISA Kit | XRCC1 elisa kit
Rat DNA repair protein XRCC1, XRCC1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
plays a role in base-excision repair; displays decreased mRNA expression in early embryos treated with the anticancer alkylating agent cyclophosphamide [RGD, Feb 2006]
Uniprot Description
XRCC1: Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF. Interacts with APEX1; the interaction is induced by SIRT1 and increases with the acetylated form of APEX1.
Protein type: DNA repair, damage
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; enzyme binding; damaged DNA binding
Biological Process: response to drug; response to organic substance; single strand break repair; base-excision repair; hippocampus development; response to hypoxia; DNA repair; response to DNA damage stimulus
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Product Notes
The Rat XRCC1 xrcc1 (Catalog #AAA9322782) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322782 ELISA Kit recognizes Rat XRCC1. It is sometimes possible for the material contained within the vial of "X-ray repair complementing defective repair in Chinese hamster cells 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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