Glutathione S-Transferase Omega 1 (GST-01) Western Blot Control | GST-01 western blot control
Glutathione S-Transferase Omega 1 (GST-01) (Western Blot Control)
Gene Names
GSTO1; SPG-R; GSTO 1-1
Purity
>= 95% (SDS PAGE)
Synonyms
Glutathione S-Transferase Omega 1 (GST-01); Glutathione S-Transferase Omega 1 (GST-01) (Western Blot Control); GSTTLp28; P28; glutathione S-transferase omega 1-1; glutathione transferase omega; glutathione transferase omega 1; glutathione-S-transferase like; Monomethyl Arsenous Reductase; GST01 140D (Western Blot Control); GST-01 western blot control
Purity/Purification
>= 95% (SDS PAGE)
Form/Format
Liquid
Sequence Length
241
Buffer
Buffered 50% glycerol
Related Product Information for GST-01 western blot control
GSTO1 is a member of the theta class glutathione S-transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-to-aspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation. Recombinant GSTO1 140D comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 140D mutant mature protein, which is expressed in E Coli with an amino-terminal hexahistidine tag.
Product Categories/Family for GST-01 western blot control
References
Whitbread, A. K. et al., Methods in Enzymology 2005; 401: 78-99 Kolsch, H. et al., Neurology 2004; 63: 2255-2260
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
27,419 Da
NCBI Official Full Name
glutathione S-transferase omega
NCBI Official Symbol
GSTO1
NCBI Official Synonym Symbols
SPG-R; GSTO 1-1
NCBI Protein Information
glutathione S-transferase omega-1
UniProt Protein Name
Glutathione S-transferase omega-1
UniProt Gene Name
GSTO1
UniProt Synonym Gene Names
MMA(V) reductase; SPG-R
UniProt Entry Name
GSTO1_PIG
Uniprot Description
Function: Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Subunit structure: Homodimer. Ref.1
Subcellular location: Cytoplasm Ref.1.
Tissue specificity: Most abundant in the liver and skeletal muscle; also expressed in heart, diaphragm, colon, thymus, kidney, lung, ovaries, spleen, intestine and pancreas. Ref.1
Sequence similarities: Belongs to the GST superfamily. Omega family.Contains 1 GST C-terminal domain.Contains 1 GST N-terminal domain.
Mass spectrometry: Molecular mass is 27328±3 Da from positions 1 - 241. Determined by ESI. Ref.1
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Product Notes
The GST-01 gsto1 (Catalog #AAA343035) is a Western Blot Control and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Glutathione S-Transferase Omega 1 (GST-01), Western Blot Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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