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mRNA-decapping protein g5R (War-112) Recombinant Protein | War-112 recombinant protein

Recombinant African swine fever virus mRNA-decapping protein g5R (War-112)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
mRNA-decapping protein g5R (War-112); Recombinant African swine fever virus mRNA-decapping protein g5R (War-112); War-112 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-246, Full length protein
Sequence
MQLKTSIGLITCRMNTQNNQIETILVQKRYSLAFSEFIHCHYSINANQGHLIKMFNNMTINERLLVKTLDFDRMWYHIWIETPVYELYHKKYQKFRKNWLLPDNGKKLISLINQAKGSGTLLWEIPKGKPKEDESDLTCAIREFEEETGITREYYQILPEFKKSMSYFDGKTEYKHIYFLAMLCKSLEEPNMNLSLQYENRIAEISKISWQNMEAVRFISKRQSLNLEPIIGPAFNFIKNYLRYKH
Sequence Length
246
Species
African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
29,404 Da
NCBI Official Full Name
mRNA-decapping protein g5R
UniProt Protein Name
mRNA-decapping protein g5R
UniProt Gene Name
War-112
UniProt Synonym Gene Names
DIPP

Uniprot Description

Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis. In addition to the mRNA cap, g5R also efficiently hydrolyzes diphosphoinositol polyphosphates. Down-regulation of the level of PP-InsP5 (diphosphoinositol pentakisphosphate) may play a role in viral manipulation of the cellular secretory pathway, a step necessary for the formation of virions ().

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Product Notes

The War-112 war-112 (Catalog #AAA1169373) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-246, Full length protein. The amino acid sequence is listed below: MQLKTSIGLI TCRMNTQNNQ IETILVQKRY SLAFSEFIHC HYSINANQGH LIKMFNNMTI NERLLVKTLD FDRMWYHIWI ETPVYELYHK KYQKFRKNWL LPDNGKKLIS LINQAKGSGT LLWEIPKGKP KEDESDLTCA IREFEEETGI TREYYQILPE FKKSMSYFDG KTEYKHIYFL AMLCKSLEEP NMNLSLQYEN RIAEISKISW QNMEAVRFIS KRQSLNLEPI IGPAFNFIKN YLRYKH. It is sometimes possible for the material contained within the vial of "mRNA-decapping protein g5R (War-112), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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