Human vacuolar protein sorting 18 homolog (S. cerevisiae) ELISA Kit | VPS18 elisa kit
Human Vacuolar protein sorting-associated protein 18 homolog, VPS18 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008]
Uniprot Description
VPS18: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Belongs to the VPS18 family.
Protein type: Ligase; Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 15q14-q15
Cellular Component: lysosomal membrane; late endosome membrane; lysosome; early endosome; late endosome; actin filament; endosome
Molecular Function: protein binding, bridging; protein binding; syntaxin binding; metal ion binding; actin binding
Biological Process: intracellular protein transport; entry of virus into host cell; endosome organization and biogenesis; lysosome organization and biogenesis; vesicle docking during exocytosis
Research Articles on VPS18
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Product Notes
The Human VPS18 vps18 (Catalog #AAA9328207) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328207 ELISA Kit recognizes Human VPS18. It is sometimes possible for the material contained within the vial of "vacuolar protein sorting 18 homolog (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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