Minor nucleoprotein VP30 (VP30) Recombinant Protein | VP30 recombinant protein

Recombinant Zaire ebolavirus Minor nucleoprotein VP30 (VP30)

Cat. Num. AAA1288327

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Minor nucleoprotein VP30 (VP30); Recombinant Zaire ebolavirus Minor nucleoprotein VP30 (VP30); Transcription activator VP30; VP30 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-288. Full length
• Sequence: MEASYERGRPRAARQHSRDGHDHHVRARSSSRENYRGEYRQSRSASQVRVPTVFHKKRVEPLTVPPAPKDICPTLKKGFLCDSSFCKKDHQLESLTDRELLLLIARKTCGSVEQQLNITAPKDSRLANPTADDFQQEEGPKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLCETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVPQSDNEEASTNPGTCSWSDEGTP
• Sequence Length: 288

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for VP30 recombinant protein

Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA st-loop at the transcription start site of the first gene. Binds to RNA.

References

Chain P.S.G., Ichou M.A., Malfatti S.A., Hajjaj A., Vergez L.M., Paragas J., Do L.H., Jahrling P.B., Smith K.L., McCready P.M., Ibrahim M.S.Crystal structure of the C-terminal domain of Ebola virus VP30 reveals a role in transcription and nucleocapsid association.Hartlieb B., Muziol T., Weissenhorn W., Becker S.Proc. Natl. Acad. Sci. U.S.A. 104:624-629(2007)

NCBI and Uniprot Product Information

• NCBI GI #: 10313997
• NCBI GeneID: 911826
• NCBI Accession #: NP_066249.1
• NCBI GenBank Nucleotide #: NC_002549.1
• UniProt Accession #: Q77DJ5; AJP14348
• Molecular Weight: 34.5 kDa
• NCBI Official Full Name: minor nucleoprotein
• NCBI Official Symbol: VP30
• NCBI Protein Information: minor nucleoprotein; polymerase complex protein
• UniProt Protein Name: Minor nucleoprotein VP30
• Protein Family: Minor nucleoprotein
• UniProt Gene Name: VP30
• UniProt Entry Name: VP30_EBOZ5

Uniprot Description

Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA stem-loop at the transcription start site of the first gene. Binds to RNA ().