Vesicular Overexpressed in Cancer Recombinant Protein | VOPP1 recombinant protein
Recombinant Human Vesicular Overexpressed in Cancer, Prosurvival Protein 1
Gene Names
VOPP1; ECOP; GASP
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Vesicular Overexpressed in Cancer; Recombinant Human Vesicular Overexpressed in Cancer; Prosurvival Protein 1; VOPP1 Human; Prosurvival Protein 1 Human Recombinant; Vesicular overexpressed in cancer prosurvival protein 1; EGFR-coamplified and overexpressed protein; ECop; Glioblastoma-amplified secreted protein; Putative NF-kappa-B-activating protein 055N; VOPP1; ECOP; GASP; FLJ20532; DKFZp564K0822; VOPP1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
The VOPP1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.2M NaCl.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK.
Sequence Length
155
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for VOPP1 recombinant protein
Description: VOPP1 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 112 amino acids (82-172 a.a.) and having a molecular mass of 12kDa. The VOPP1 is purified by proprietary chromatographic techniques.
Introduction: Vesicular overexpressed in cancer prosurvival protein 1 (VOPP1) has been previously shown to be over-expressed in human glioblastoma multiform and squamous cell carcinoma. VOPP1 is a crucial regulator of NF-kappaB signaling, and this high-level, amplification-mediated VOPP1 expression, such as that occurring in tumors with amplified EGFR, might impact the resistance to apoptosis.
Introduction: Vesicular overexpressed in cancer prosurvival protein 1 (VOPP1) has been previously shown to be over-expressed in human glioblastoma multiform and squamous cell carcinoma. VOPP1 is a crucial regulator of NF-kappaB signaling, and this high-level, amplification-mediated VOPP1 expression, such as that occurring in tumors with amplified EGFR, might impact the resistance to apoptosis.
Product Categories/Family for VOPP1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,381 Da
NCBI Official Full Name
vesicular, overexpressed in cancer, prosurvival protein 1 isoform 2
NCBI Official Synonym Full Names
vesicular, overexpressed in cancer, prosurvival protein 1
NCBI Official Symbol
VOPP1
NCBI Official Synonym Symbols
ECOP; GASP
NCBI Protein Information
vesicular, overexpressed in cancer, prosurvival protein 1; EGFR-coamplified and overexpressed protein; Glioblastoma-amplified secreted protein; hypothetical protein DKFZp564K0822; putative NF-kappa-B-activating protein 055N
UniProt Protein Name
Vesicular, overexpressed in cancer, prosurvival protein 1
Protein Family
UniProt Gene Name
VOPP1
UniProt Synonym Gene Names
ECOP; GASP; ECop
UniProt Entry Name
VOPP1_HUMAN
Uniprot Description
ECOP: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. Belongs to the VOPP1/ECOP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p11.2
Cellular Component: cytoplasmic vesicle membrane; endosome
Molecular Function: signal transducer activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; signal transduction
Research Articles on VOPP1
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Product Notes
The VOPP1 vopp1 (Catalog #AAA144361) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MRRRMY PPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK.. It is sometimes possible for the material contained within the vial of "Vesicular Overexpressed in Cancer, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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