Western Blot (WB)
(ECOP Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ECOP antibody detected the ECOP protein (arrow).)
Rabbit anti-Mouse ECOP Polyclonal Antibody | anti-ECOP antibody
ECOP, ID (VOPP1, ECOP, GASP, Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N) (APC)
Gene Names
VOPP1; ECOP; GASP
Reactivity
Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ECOP; Polyclonal Antibody; ID (VOPP1; GASP; Vesicular; overexpressed in cancer; prosurvival protein 1; EGFR-coamplified and overexpressed protein; Glioblastoma-amplified secreted protein; Putative NF-kappa-B-activating protein 055N) (APC); VOPP1; Putative NF-kappa-B-activating protein 055N; anti-ECOP antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-ECOP antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ECOP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-103 amino acids from the Central region of human ECOP.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(ECOP Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ECOP antibody detected the ECOP protein (arrow).)
Western Blot (WB)
(ECOP Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ECOP antibody detected the ECOP protein (arrow).)
Related Product Information for anti-ECOP antibody
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
Product Categories/Family for anti-ECOP antibody
References
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010). Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010). Baras, A., et al. Oncogene 28(32):2919-2924(2009). Chechlinska, M., et al. BMC Genomics 10, 261 (2009): Brem, H., et al. Mol. Med. 13 (1-2), 30-39 (2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,381 Da
NCBI Official Full Name
vesicular, overexpressed in cancer, prosurvival protein 1 isoform 1
NCBI Official Synonym Full Names
vesicular, overexpressed in cancer, prosurvival protein 1
NCBI Official Symbol
VOPP1
NCBI Official Synonym Symbols
ECOP; GASP
NCBI Protein Information
vesicular, overexpressed in cancer, prosurvival protein 1; hypothetical protein DKFZp564K0822; Glioblastoma-amplified secreted protein; EGFR-coamplified and overexpressed protein; putative NF-kappa-B-activating protein 055N
UniProt Protein Name
Vesicular, overexpressed in cancer, prosurvival protein 1
UniProt Gene Name
VOPP1
UniProt Synonym Gene Names
ECOP; GASP; ECop
UniProt Entry Name
VOPP1_HUMAN
Uniprot Description
ECOP: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. Belongs to the VOPP1/ECOP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p11.2
Cellular Component: cytoplasmic vesicle membrane; endosome
Molecular Function: signal transducer activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; signal transduction
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Product Notes
The ECOP vopp1 (Catalog #AAA6294259) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ECOP, ID (VOPP1, ECOP, GASP, Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N) (APC) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ECOP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ECOP vopp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECOP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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