Mouse vestigial like 2 (Drosophila) ELISA Kit | VGLL2 elisa kit

Mouse Transcription cofactor vestigial-like protein 2, VGLL2 ELISA Kit

Cat. Num. AAA9330290

• Gene Names: Vgll2; Vito1; vgl-2; VITO-1; C130057C21Rik
• Reactivity: Mouse
• Synonyms: vestigial like 2 (Drosophila); Mouse Transcription cofactor vestigial-like protein 2; VGLL2 ELISA Kit; Mouse Transcription cofactor vestigial-like protein 2 (VGLL2) ELISA kit; RP1-179P9.2; VGL2; VITO1; transcription cofactor vestigial-like 2; vestigial-like 2; VGLL2 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 24418891
• NCBI GeneID: 215031
• NCBI Accession #: NP_722481.1
• NCBI GenBank Nucleotide #: NM_153786.2
• UniProt Accession #: Q8BGW8; Q8BWB4
• Molecular Weight: 34,064 Da
• NCBI Official Full Name: transcription cofactor vestigial-like protein 2 isoform 1
• NCBI Official Synonym Full Names: vestigial like 2 homolog (Drosophila)
• NCBI Official Symbol: Vgll2
• NCBI Official Synonym Symbols: Vito1; vgl-2; VITO-1; C130057C21Rik
• NCBI Protein Information: transcription cofactor vestigial-like protein 2
• UniProt Protein Name: Transcription cofactor vestigial-like protein 2
• Protein Family: Transcription cofactor vestigial-like protein
• UniProt Gene Name: Vgll2
• UniProt Synonym Gene Names: Vgl2; Vito1; Vgl-2
• UniProt Entry Name: VGLL2_MOUSE

NCBI Description

This gene is a member of the Vestigial-like (Vgl) gene family and is upregulated during muscle differentiation. The product of this gene interacts with and modifies the DNA-binding properties of the transcription factor, TEF-1, and is important for muscle tissue development. Reduced expression of this gene leads to a reduction in the terminal differentiation of muscle cells. Alternate splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]

Uniprot Description

VGLL2: May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles. Belongs to the vestigial family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Cellular Component: cytoplasm; nucleus

Molecular Function: protein C-terminus binding; protein binding; transcription coactivator activity

Biological Process: skeletal muscle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter