Chicken Vinculin ELISA Kit | VCL elisa kit

Chicken Vinculin ELISA Kit

Cat. Num. AAA2885954

• Reactivity: Chicken
• Synonyms: Vinculin; Chicken Vinculin ELISA Kit; Metavinculin; VCL; VINC1; VCL elisa kit

• Reactivity: Chicken
• Sequence Length: 1066

• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 45382123
• NCBI GeneID: 396422
• NCBI Accession #: NP_990772.1
• NCBI GenBank Nucleotide #: NM_205441.1
• UniProt Accession #: P12003; Q91024
• Molecular Weight: 116,999 Da
• NCBI Official Full Name: vinculin
• NCBI Official Synonym Full Names: vinculin
• NCBI Official Symbol: VCL
• NCBI Protein Information: vinculin
• UniProt Protein Name: Vinculin
• Protein Family: Vinculin
• UniProt Gene Name: VCL
• UniProt Synonym Gene Names: VINC1
• UniProt Entry Name: VINC_CHICK

Uniprot Description

Vinculin: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. Exhibits self-association properties. Interacts with NRAP and SORBS1. Interacts with TLN1. Interacts with SYNM. Interacts with CTNNB1 and this interaction is necessary for its localization to the cell-cell junctions and for its function in regulating cell surface expression of E-cadherin. Metavinculin is muscle-specific. Belongs to the vinculin/alpha-catenin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cell adhesion; Cytoskeletal

Cellular Component: actin cytoskeleton; adherens junction; brush border; cell; costamere; fascia adherens; focal adhesion; intercellular junction; lipid raft; mitochondrial inner membrane; muscle tendon junction; neuromuscular junction; plasma membrane; protein complex; sarcolemma; stress fiber; Z disc; zonula adherens

Molecular Function: actin filament binding; alpha-actinin binding; alpha-catenin binding; beta-catenin binding; cadherin binding; muscle alpha-actinin binding; protein binding; protein homodimerization activity; structural molecule activity; ubiquitin protein ligase binding; vinculin binding

Biological Process: apical junction assembly; axon extension; lamellipodium biogenesis; morphogenesis of an epithelium; regulation of cell migration