Typical Testing Data/Standard Curve (for reference only)
Rat Vinculin ELISA Kit | Vcl elisa kit
Rat Vinculin ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
Vinculin: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. Exhibits self-association properties. Interacts with NRAP and SORBS1. Interacts with TLN1. Interacts with SYNM. Interacts with CTNNB1 and this interaction is necessary for its localization to the cell-cell junctions and for its function in regulating cell surface expression of E-cadherin. Metavinculin is muscle-specific. Belongs to the vinculin/alpha-catenin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal; Cell adhesion
Cellular Component: actin cytoskeleton; actin filament; adherens junction; brush border; cell; cell-cell adherens junction; costamere; cytoplasm; fascia adherens; focal adhesion; intercellular junction; lipid raft; plasma membrane; protein complex; sarcolemma; stress fiber; Z disc; zonula adherens
Molecular Function: actin binding; actin filament binding; alpha-catenin binding; Rho GTPase binding; structural molecule activity; ubiquitin protein ligase binding
Biological Process: apical junction assembly; axon extension; cell adhesion; lamellipodium biogenesis; morphogenesis of an epithelium; regulation of cell migration
Research Articles on Vcl
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Product Notes
The Rat Vcl vcl (Catalog #AAA2880562) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880562 ELISA Kit recognizes Rat Vcl. It is sometimes possible for the material contained within the vial of "Vinculin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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