General vesicular transport factor p115 (Uso1) Recombinant Protein | Uso1 recombinant protein

Recombinant Rat General vesicular transport factor p115 (Uso1) , partial

• Gene Names: Uso1; TAP; Vdp
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: General vesicular transport factor p115 (Uso1); Recombinant Rat General vesicular transport factor p115 (Uso1); partial; Uso1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 959

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Uso1 recombinant protein

This protein is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis
medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.

NCBI and Uniprot Product Information

• NCBI GI #: 9507177
• NCBI GeneID: 56042
• NCBI Accession #: NP_062252.1
• NCBI GenBank Nucleotide #: NM_019379.1
• UniProt Accession #: P41542
• Molecular Weight: 107,162 Da
• NCBI Official Full Name: general vesicular transport factor p115
• NCBI Official Synonym Full Names: USO1 vesicle transport factor
• NCBI Official Symbol: Uso1
• NCBI Official Synonym Symbols: TAP; Vdp
• NCBI Protein Information: general vesicular transport factor p115
• UniProt Protein Name: General vesicular transport factor p115
• Protein Family: General vesicular transport factor
• UniProt Gene Name: Uso1
• UniProt Synonym Gene Names: Vdp; TAP

NCBI Description

tethering protein involved with transcytotic vesicle transport, including ER to Golgi and between the Golgi stacks [RGD, Feb 2006]

Uniprot Description

General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane (PubMed:7831323, PubMed:7831324, PubMed:10679020). May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (PubMed:7831323, PubMed:7831324, PubMed:10679020).