Cytochrome b-c1 complex subunit 8 Recombinant Protein | QCR8 recombinant protein

Recombinant Human Cytochrome b-c1 complex subunit 8

Cat. Num. AAA9421664

• Gene Names: UQCRQ; QPC; QCR8; QP-C; UQCR7; MC3DN4
• Reactivity: Human
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: Cytochrome b-c1 complex subunit 8; Recombinant Human Cytochrome b-c1 complex subunit 8; Complex III subunit omplex III subunit VIIIUbiquinol-cytochrome c reductase complex 9.5 kDa proteinUbiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; QCR8 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Partial of the Full Length of 2-82aa, 2-78aa

• Tag Info: GST-tag
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for QCR8 recombinant protein

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.

NCBI and Uniprot Product Information

• NCBI GI #: 83367083
• NCBI GeneID: 27089
• NCBI Accession #: NP_055217.2
• NCBI GenBank Nucleotide #: NM_014402.4
• UniProt Accession #: O14949; Q5FVE2; Q9BV88; Q9T2V7
• Molecular Weight: 36.7kD
• NCBI Official Full Name: cytochrome b-c1 complex subunit 8
• NCBI Official Synonym Full Names: ubiquinol-cytochrome c reductase complex III subunit VII
• NCBI Official Symbol: UQCRQ
• NCBI Official Synonym Symbols: QPC; QCR8; QP-C; UQCR7; MC3DN4
• NCBI Protein Information: cytochrome b-c1 complex subunit 8
• UniProt Protein Name: Cytochrome b-c1 complex subunit 8
• Protein Family: Cytochrome b-c1 complex
• UniProt Gene Name: UQCRQ

NCBI Description

This gene encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain. [provided by RefSeq, Jul 2008]

Uniprot Description

UQCRQ: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone. Defects in UQCRQ are a cause of mitochondrial complex III deficiency (MT-C3D). A disorder of the mitochondrial respiratory chain resulting in a highly variable phenotype depending on which tissues are affected. Clinical features include mitochondrial encephalopathy, psychomotor retardation, ataxia, severe failure to thrive, liver dysfunction, renal tubulopathy, muscle weakness and exercise intolerance. Belongs to the UQCRQ/QCR8 family.

Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrion

Molecular Function: ubiquinol-cytochrome-c reductase activity

Biological Process: mitochondrial electron transport, ubiquinol to cytochrome c

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 4