NCBI and Uniprot Product Information
Uniprot Description
ULBP3: Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1. Belongs to the MHC class I family.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 6q25
Cellular Component: anchored to plasma membrane; plasma membrane
Molecular Function: peptide antigen binding; natural killer cell lectin-like receptor binding
Biological Process: antigen processing and presentation of peptide antigen via MHC class I; regulation of immune response; viral reproduction; natural killer cell mediated cytotoxicity; natural killer cell activation
Research Articles on ULBP3
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Product Notes
The Goat ULBP3 ulbp3 (Catalog #AAA755596) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA755596 ELISA Kit recognizes Goat ULBP3. It is sometimes possible for the material contained within the vial of "UL16 Binding protein 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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