Cytomegalovirus pP28 (UL99) Recombinant Protein | CMV pp28 recombinant protein
Cytomegalovirus pP28 (UL99) Recombinant
Recombinant CMV Glycoprotein B contains an N terminal GST purification tag and migrates as an approximately 30kDa protein reducing conditions in SDS-PAGE.
NCBI and Uniprot Product Information
Uniprot Description
Function: Tegument protein that may play a role in the nucleocapsid secondary envelopment at the trans-Golgi network during virus morphogenesis
Potential. Ref.5 Ref.6
Subunit structure: Interacts with capsid-binding protein UL94
By similarity.
Subcellular location: Virion tegument
By similarity. Virion membrane; Lipid-anchor
By similarity. Host cell membrane; Lipid-anchor; Cytoplasmic side
By similarity. Host Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side
Potential. Host nucleus membrane
By similarity. Note: Virion membrane-associated tegument protein. Associates with host membrane lipids rafts
By similarity. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN)
By similarity. Ref.6
Domain: The acidic region is required for efficient packaging. It is also involved in recycling the protein from the plasma membrane to the Golgi apparatus, and in the interaction with the capsid-binding protein UL94 (HHV-1 UL16 homolog)
By similarity.
Post-translational modification: Myristoylation and palmitoylation (probably on one or more of the nearby cysteines at the N-terminus) enable membrane-binding and Golgi apparatus-specific targeting and are essential for efficient packaging
By similarity.Phosphorylated. Packaging is selective for underphosphorylated forms
By similarity. Ref.1
Sequence similarities: Belongs to the herpesviridae HHV-1 UL11 family.
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Product Notes
The CMV pp28 ul99 (Catalog #AAA553165) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. CMV pp28 antigen is suitable for ELISA and Western blots, excellent antigen for detection of CMV with minimal specificity problems. . Researchers should empirically determine the suitability of the CMV pp28 ul99 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytomegalovirus pP28 (UL99), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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