Rabbit anti-Human CD163L1 Polyclonal Antibody | anti-CD163L1 antibody

CD163L1, CT (CD163L1, CD163B, M160, Scavenger receptor cysteine-rich type 1 protein M160, CD163 antigen-like 1, CD163b) (APC)

Cat. Num. AAA6282818

• Gene Names: CD163L1; M160; CD163B
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: CD163L1; Polyclonal Antibody; CT (CD163L1; CD163B; M160; Scavenger receptor cysteine-rich type 1 protein M160; CD163 antigen-like 1; CD163b) (APC); CD163b; anti-CD163L1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CD163L1.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-CD163L1 antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1401-1430 in the C-terminal region of human CD163L1, UniProt Accession #Q9NR16.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in NCI-H292 cell line lysates (35ug/lane) usingMBS6005334. This demonstrates that MBS6005334 detected the CD163L1 protein (arrow).)

Related Product Information for anti-CD163L1 antibody

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.

Product Categories/Family for anti-CD163L1 antibody

Antibodies; Receptors; Scavenger

References

1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 2. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 3. Van Gorp, H., et al. J. Virol. 84(6):3101-3105(2010). 4. Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004). 5. Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 50659091
• NCBI GeneID: 283316
• NCBI Accession #: NP_777601.2
• NCBI GenBank Nucleotide #: NM_174941.5
• UniProt Accession #: Q9NR16; Q2M3B7; Q6UWC2; B4E0G7; C9JHR7; E7EVK4
• Molecular Weight: 159,239 Da
• NCBI Official Full Name: scavenger receptor cysteine-rich type 1 protein M160 isoform 2
• NCBI Official Synonym Full Names: CD163 molecule-like 1
• NCBI Official Symbol: CD163L1
• NCBI Official Synonym Symbols: M160; CD163B
• NCBI Protein Information: scavenger receptor cysteine-rich type 1 protein M160; CD163 antigen B; CD163 antigen-like 1
• UniProt Protein Name: Scavenger receptor cysteine-rich type 1 protein M160
• Protein Family: Scavenger receptor cysteine-rich type 1 protein
• UniProt Gene Name: CD163L1
• UniProt Synonym Gene Names: CD163B; M160; UNQ6434/PRO23202
• UniProt Entry Name: C163B_HUMAN

NCBI Description

This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Uniprot Description

CD163L1: a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: integral to membrane; extracellular region; plasma membrane

Molecular Function: scavenger receptor activity

Biological Process: receptor-mediated endocytosis