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SDS-Page

uBXN2B recombinant protein

uBXN2B, 1-331aa, Human, His tag, E Coli

Gene Names
UBXN2B; p37
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
uBXN2B; 1-331aa; Human; His tag; E Coli; uBX domain-containing protein 2B; p37; uBXN2B recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Concentration
0.5 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEGGGP EPGEQERRSS GPRPPSARDL QLALAELYED EVKCKSSKSN RPKATVFKSP RTPPQRFYSS EHEYSGLNIV RPSTGKIVNE LFKEAREHGA VPLNEATRAS GDDKSKSFTG GGYRLGSSFC KRSEYIYGEN QLQDVQILLK LWSNGFSLDD GELRPYNEPT NAQFLESVKR GEIPLELQRL VHGGQVNLDM EDHQDQEYIK PRLRFKAFSG EGQKLGSLTP EIVSTPSSPE EEDKSILNAV VLIDDSVPTT KIQIRLADGS RLIQRFNSTH RILDVRNFIV QSRPEFAALD FILVTSFPNK ELTDESLTLL EADILNTVLL QQLK
Sequence Length
331
Applicable Applications for uBXN2B recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for uBXN2B recombinant protein
uBX domain-containing protein 2B, also known as uBXN2B, is a 331 amino acid protein that contains one uBX domain and one SEP domain. uBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, uBXN2B forms a complex that has membrane fusion activity. Recombinant human uBXN2B protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for uBXN2B recombinant protein
References
uchiyama K., et al. (2006) Dev Cell. 11:803-816.; Tang D., et al. (2008) J Biol Chem. 283:6085-6094.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39.5kDa (354aa), confirmed by MALDI-TOF
NCBI Official Full Name
UBX domain-containing protein 2B isoform 1
NCBI Official Synonym Full Names
UBX domain protein 2B
NCBI Official Symbol
UBXN2B
NCBI Official Synonym Symbols
p37
NCBI Protein Information
UBX domain-containing protein 2B
UniProt Protein Name
UBX domain-containing protein 2B
UniProt Gene Name
UBXN2B

Uniprot Description

Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.

Research Articles on uBXN2B

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Product Notes

The uBXN2B ubxn2b (Catalog #AAA204971) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's uBXN2B can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the uBXN2B ubxn2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSMAEGGGP EPGEQERRSS GPRPPSARDL QLALAELYED EVKCKSSKSN RPKATVFKSP RTPPQRFYSS EHEYSGLNIV RPSTGKIVNE LFKEAREHGA VPLNEATRAS GDDKSKSFTG GGYRLGSSFC KRSEYIYGEN QLQDVQILLK LWSNGFSLDD GELRPYNEPT NAQFLESVKR GEIPLELQRL VHGGQVNLDM EDHQDQEYIK PRLRFKAFSG EGQKLGSLTP EIVSTPSSPE EEDKSILNAV VLIDDSVPTT KIQIRLADGS RLIQRFNSTH RILDVRNFIV QSRPEFAALD FILVTSFPNK ELTDESLTLL EADILNTVLL QQLK. It is sometimes possible for the material contained within the vial of "uBXN2B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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