Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/35,)
Rabbit anti-Human UBXN2B Polyclonal Antibody | anti-UBXN2B antibody
UBXN2B Antibody
Gene Names
UBXN2B; p37
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
UBXN2B; Polyclonal Antibody; UBXN2B Antibody; p37; anti-UBXN2B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total UBXN2B protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
2 mg/ml (varies by lot)
Sequence Length
331
Applicable Applications for anti-UBXN2B antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:30-1:150
Immunogen
Fusion protein of human UBXN2B
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/35,)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/35,)
Related Product Information for anti-UBXN2B antibody
UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity.Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
Product Categories/Family for anti-UBXN2B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,077 Da
NCBI Official Full Name
UBX domain-containing protein 2B
NCBI Official Synonym Full Names
UBX domain protein 2B
NCBI Official Symbol
UBXN2B
NCBI Official Synonym Symbols
p37
NCBI Protein Information
UBX domain-containing protein 2B
UniProt Protein Name
UBX domain-containing protein 2B
Protein Family
UniProt Gene Name
UBXN2B
UniProt Entry Name
UBX2B_HUMAN
Uniprot Description
UBXN2B: Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Belongs to the NSFL1C family.
Protein type: Adaptor/scaffold; Endoplasmic reticulum
Chromosomal Location of Human Ortholog: 8q12.1
Cellular Component: cytosol; nucleus
Molecular Function: protein binding; ubiquitin binding
Biological Process: Golgi organization and biogenesis; nuclear envelope reassembly; proteasomal ubiquitin-dependent protein catabolic process
Similar Products
Product Notes
The UBXN2B ubxn2b (Catalog #AAA9415399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UBXN2B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UBXN2B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:30-1:150. Researchers should empirically determine the suitability of the UBXN2B ubxn2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UBXN2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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