Ubiquitin Associated Protein 1 Recombinant Protein | UBAP1 recombinant protein

Recombinant Ubiquitin Associated Protein 1 (UBAP1)

Cat. Num. AAA2033148

• Gene Names: UBAP1; UAP; UBAP; NAG20; UBAP-1
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 90%
• Synonyms: Ubiquitin Associated Protein 1; Recombinant Ubiquitin Associated Protein 1 (UBAP1); NAG20; UAP; UBAP; Nasopharyngeal carcinoma-associated gene 20 protein; UBAP1 recombinant protein

• Host: E Coli
• Purity/Purification: > 90%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: MASKKLGADF HGTFSYLDDV PFKTGDKFKT PAKVGLPIGF SLPDCLQVVREVQYDFSLEK KTIEWAEEIK KIEEAEREAE CKIAEAEAKV NSKSGPEGDSKMSFSKTHST ATMPPPINPI LASLQHNSIL TPTRVSSSAT KQKVLSPPHIKADFNLADFE CEEDPFDNLE LKTIDEKEEL RNILVGTTGP IMAQLLDNNLPRGGSGSVLQ DEEVLASLER ATLDFKPLHK PNGFITLPQL GNCEKMSLSSKVSLPPIPAV SNIKSLSFPK LDSDDSNQKT AKLASTFHST SCLRN
• Sequence Length: 502

• Applicable Applications for UBAP1 recombinant protein: SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP).
• Predicted Molecular Mass: 36.0kDa
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Endotoxin Level: <1.0EU per 1 ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Fragment: Met1~Asn295
• Organism Species: Human
• Tag: two N-terminal Tags, His-tag and T7-tag
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 8394499
• NCBI GeneID: 51271
• NCBI Accession #: NP_057609.2
• NCBI GenBank Nucleotide #: NM_016525.4
• Molecular Weight: 61,845 Da
• NCBI Official Full Name: ubiquitin-associated protein 1 isoform 1
• NCBI Official Synonym Full Names: ubiquitin associated protein 1
• NCBI Official Symbol: UBAP1
• NCBI Official Synonym Symbols: UAP; UBAP; NAG20; UBAP-1
• NCBI Protein Information: ubiquitin-associated protein 1
• UniProt Protein Name: Ubiquitin-associated protein 1
• Protein Family: Ubiquitin-associated protein
• UniProt Gene Name: UBAP1
• UniProt Synonym Gene Names: UBAP-1
• UniProt Entry Name: UBAP1_HUMAN

NCBI Description

This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Uniprot Description

UBAP1: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: cytoplasm; cytosol; Golgi apparatus; plasma membrane

Molecular Function: protein binding; ubiquitin binding

Biological Process: protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body pathway