Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using TPH2 (Phospho-Ser19) antibody.)
TPH2 Antibody | anti-TPH2 antibody
TPH2 (Phospho-Ser19) Antibody
Gene Names
TPH2; NTPH; ADHD7
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Synonyms
TPH2; TPH2 (Phospho-Ser19) Antibody; ADHD7; FLJ37295; MGC138871; MGC138872; Neuronal tryptophan hydroxylase; NTPH; Tryptophan 5-hydroxylase 2; Tryptophan 5-monooxygenase 2; tryptophan hydroxylase 2; anti-TPH2 antibody
Reactivity
Human, Mouse, Rat
Specificity
TPH2 (Phospho-Ser19) antibody detects endogenous levels of TPH2 only when phosphorylated at serine 19.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
490
Applicable Applications for anti-TPH2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:40000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human TPH2 around the phosphorylation site of serine 19.
All Sites
Human: Ser19
Mouse: Ser19
Rat: Ser19
Mouse: Ser19
Rat: Ser19
Preparation and Storage
Store at-20 degree C for 1 year.
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using TPH2 (Phospho-Ser19) antibody.)
Western Blot (WB)
(Western blot analysis of extracts from HepG2 cells, using TPH2 (Phospho-Ser19) antibody.)
Product Categories/Family for anti-TPH2 antibody
References
Walther D.J., Science 299:76-76(2003). Scherer S.E., Nature 440:346-351(2006). Scherer S.E., Nature 440:346-351(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,242 Da
NCBI Official Full Name
tryptophan 5-hydroxylase 2
NCBI Official Synonym Full Names
tryptophan hydroxylase 2
NCBI Official Symbol
TPH2
NCBI Official Synonym Symbols
NTPH; ADHD7
NCBI Protein Information
tryptophan 5-hydroxylase 2
UniProt Protein Name
Tryptophan 5-hydroxylase 2
Protein Family
UniProt Gene Name
TPH2
UniProt Synonym Gene Names
NTPH
NCBI Description
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]
Research Articles on TPH2
Similar Products
Product Notes
The TPH2 tph2 (Catalog #AAA858310) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TPH2 (Phospho-Ser19) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TPH2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:40000. Researchers should empirically determine the suitability of the TPH2 tph2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TPH2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
