Thiosulfate sulfurtransferase Recombinant Protein | TST recombinant protein

Thiosulfate sulfurtransferase, 1-297aa, Human, E Coli

Cat. Num. AAA203562

• Gene Names: TST; RDS
• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: Thiosulfate sulfurtransferase; 1-297aa; Human; E Coli; RDS; TST; Rhodanese; Thiosulfate Sulfurtransferase; TST recombinant protein

• Host: E Coli
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MVHQVLYRAL VSTKWLAESI RTGKLGPGLR VLDASWYSPG TREARKEYLE RHVPGASFFD IEECRDTASP YEMMLPSEAG FAEYVGRLGI SNHTHVVVYD GEHLGSFYAP RVWWMFRVFG HRTVSVLNGG FRNWLKEGHP VTSEPSRPEP AVFKATLDRS LLKTYEQVLE NLESKRFQLV DSRSQGRFLG TEPEPDAVGL DSGHIRGAVN MPFMDFLTED GFEKGPEELR ALFQTKKVDL SQPLIATCRK GVTACHVALA AYLCGKPDVA VYDGSWSEWF RRAPPESRVS QGKSEKA
• Sequence Length: 297

• Applicable Applications for TST recombinant protein: SDS-PAGE
• Antigen Species: Human
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for TST recombinant protein

Thiosulfate sulfurtransferase (TST), also known as Rhodanese, is a mitochondrial enzyme that involved in cyanide detoxification and the modification of sulfur-containing enzymes. This protein contains two highly conservative domains, known as rhodanese homology domains. In mammals, most cyanide is converted to thiocyanate by this enzyme. TST also has weak mercaptopyruvate sulfurtransferase activity. Recombinant TST protein was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for TST recombinant protein

Enzymes & Proteases

References

Pallini R., et al. (1991) Biochem Biophys Res Commun. 180 (2):887-93. ; Aita N., et al. (1997) Biochem Biophys Res Commun. 231 (1):56-60.;

NCBI and Uniprot Product Information

• NCBI GI #: 17402865
• NCBI GeneID: 7263
• NCBI Accession #: NP_003303
• NCBI GenBank Nucleotide #: NM_003312.5
• UniProt Accession #: Q16762; Q6IB06; B3KRM1
• Molecular Weight: 35.6 kDa (317aa), confirmed by MALDI-TOF.
• NCBI Official Full Name: thiosulfate sulfurtransferase
• NCBI Official Synonym Full Names: thiosulfate sulfurtransferase
• NCBI Official Symbol: TST
• NCBI Official Synonym Symbols: RDS
• NCBI Protein Information: thiosulfate sulfurtransferase
• UniProt Protein Name: Thiosulfate sulfurtransferase
• Protein Family: Toxic shock syndrome toxin
• UniProt Gene Name: TST

NCBI Description

This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.