Probable tRNA-splicing endonuclease subunit sen-34 (sen-34) Recombinant Protein | sen-34 recombinant protein

Recombinant Neurospora crassa Probable tRNA-splicing endonuclease subunit sen-34 (sen-34)

Cat. Num. AAA1439104

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Probable tRNA-splicing endonuclease subunit sen-34 (sen-34); Recombinant Neurospora crassa Probable tRNA-splicing endonuclease subunit sen-34 (sen-34); sen-34 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-315, Full length
• Sequence: MSSTEDDRQVRISKIAGRYLVFDIDDVAYIRRQHGICAVFTGTMPQNPTQNVFLGLPLELYAEDAKMLLDRKVAYIADDPLEHLTQLKSMDDETRKSYLQSIKTQRRTAQLVFNEAKAQSMAKHKDKRKPKQPQPSVVVPTELPLSASSADGVAAAVDQEEEGGAEFLLESSSSKPLKTDASTPPQKPLVKEKLPAITPTTSNAMISNGTSNPDVENHTALPLYSYLNERGYFITPGLRFGGDFSVYPGDPFRYHAHYMANSYGWDEKIPMLDLVTSGRLGTAVKKSFLMGGQKPATEDSEAGELRAFCIEWAGM
• Sequence Length: 315

• Species: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 85109007
• NCBI GeneID: 3878809
• NCBI Accession #: XP_962702.1
• NCBI GenBank Nucleotide #: XM_957609.1
• UniProt Accession #: Q7SAK9
• Molecular Weight: 34,841 Da
• NCBI Official Full Name: tRNA-splicing endonuclease subunit sen34
• NCBI Official Symbol: NCU08032
• NCBI Protein Information: tRNA-splicing endonuclease subunit sen34
• UniProt Protein Name: Probable tRNA-splicing endonuclease subunit tsp-4
• UniProt Gene Name: tsp-4
• UniProt Synonym Gene Names: sen34

Uniprot Description

Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. It probably carries the active site for 3'-splice site cleavage ().