Mouse Ts translation elongation factor, mitochondrial ELISA Kit | TSFM elisa kit
Mouse Elongation factor Ts, mitochondrial, TSFM ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
EFT5: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Defects in TSFM are the cause of combined oxidative phosphorylation deficiency type 3 (COXPD3). Defects in the mitochondrial oxidative phosphorylation system result in devastating, mainly multisystem, diseases. COXPD3 symptoms include severe metabolic acidosis with encephalomyopathy or with hypertrophic cardiomyopathy. Patients show a severe defect in mitochondrial translation leading to a failure to assemble adequate amounts of three of the oxidative phosphorylation complexes. Belongs to the EF-Ts family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation elongation; Translation
Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; intracellular; nucleus
Molecular Function: translation elongation factor activity
Biological Process: translational elongation; translation
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Product Notes
The Mouse TSFM tsfm (Catalog #AAA9341323) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341323 ELISA Kit recognizes Mouse TSFM. It is sometimes possible for the material contained within the vial of "Ts translation elongation factor, mitochondrial, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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