Rat Transient receptor potential cation channel subfamily V member 1 ELISA Kit | Trpv1 elisa kit
Rat Transient receptor potential cation channel subfamily V member 1 ELISA Kit
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
ion channel that demonstrates heat-evoked membrane currents [RGD, Feb 2006]
Uniprot Description
TRPV1: a receptor for capsaicin and a non-selective cation channel that is structurally related to members of the TRP family of ion channels. Activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo.
Protein type: Membrane protein, multi-pass; Receptor, misc.; Membrane protein, integral; Channel, cation
Cellular Component: cell junction; cell soma; cytosol; dendrite; external side of plasma membrane; integral to membrane; intrinsic to plasma membrane; membrane; neuron projection; plasma membrane; postsynaptic membrane; synapse
Molecular Function: ATP binding; calcium channel activity; calcium-release channel activity; calmodulin binding; cation channel activity; cation transmembrane transporter activity; chloride channel regulator activity; excitatory extracellular ligand-gated ion channel activity; identical protein binding; ion channel activity; ligand-gated ion channel activity; phosphoprotein binding; protein binding; transmembrane receptor activity
Biological Process: behavioral response to pain; calcium ion transport; detection of chemical stimulus involved in sensory perception of pain; detection of temperature stimulus involved in sensory perception of pain; detection of temperature stimulus involved in thermoception; diet induced thermogenesis; elevation of cytosolic calcium ion concentration; fever; glutamate secretion; inflammatory response; lipid metabolic process; microglial cell activation; negative regulation of transcription from RNA polymerase II promoter; peptide secretion; positive regulation of apoptosis; positive regulation of nitric oxide biosynthetic process; response to heat; response to organic nitrogen; response to pain; response to peptide hormone stimulus; response to pH; sensory perception of mechanical stimulus; sensory perception of pain; signal transduction; smooth muscle contraction involved in micturition; thermoception; thermoregulation; urinary bladder smooth muscle contraction
Research Articles on Trpv1
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Product Notes
The Rat Trpv1 trpv1 (Catalog #AAA2880248) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880248 ELISA Kit recognizes Rat Trpv1. It is sometimes possible for the material contained within the vial of "Transient receptor potential cation channel subfamily V member 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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