Human transient receptor potential cation channel, subfamily C, member 4 associated protein ELISA Kit | TRPC4AP elisa kit
Human Short transient receptor potential channel 4-associated protein, TRPC4AP ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TRPC4AP: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 20q11.22
Cellular Component: plasma membrane
Molecular Function: protein binding; phosphatase binding
Biological Process: ubiquitin-dependent protein catabolic process; protein ubiquitination; transmembrane transport
Research Articles on TRPC4AP
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Product Notes
The Human TRPC4AP trpc4ap (Catalog #AAA9336060) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336060 ELISA Kit recognizes Human TRPC4AP. It is sometimes possible for the material contained within the vial of "transient receptor potential cation channel, subfamily C, member 4 associated protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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