TRIM72 / Tripartite Motif-Containing Protein 72 Recombinant Protein | TRIM72 recombinant protein
Human TRIM72 / Tripartite Motif-Containing Protein 72 Recombinant Protein
Gene Names
TRIM72; MG53
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
TRIM72 / Tripartite Motif-Containing Protein 72; Human TRIM72 / Tripartite Motif-Containing Protein 72 Recombinant Protein; Tripartite motif-containing protein 72; Mitsugumin-53; Mg53; MG53; TRIM72 recombinant protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
477
Applicable Applications for TRIM72 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Homooligomer; disulfide-linked. Interacts with DYSF and CAV3.
Entry Function
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
tripartite motif-containing protein 72
NCBI Official Synonym Full Names
tripartite motif containing 72
NCBI Official Symbol
TRIM72
NCBI Official Synonym Symbols
MG53
NCBI Protein Information
tripartite motif-containing protein 72
UniProt Protein Name
Tripartite motif-containing protein 72
Protein Family
UniProt Gene Name
TRIM72
UniProt Synonym Gene Names
Mg53
UniProt Entry Name
TRI72_HUMAN
Research Articles on TRIM72
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Product Notes
The TRIM72 trim72 (Catalog #AAA2903387) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TRIM72 / Tripartite Motif-Containing Protein 72 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the TRIM72 trim72 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIM72 / Tripartite Motif-Containing Protein 72, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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