Tripartite motif-containing protein 72 (TRIM72) Recombinant Protein | TRIM72 recombinant protein

Recombinant Human Tripartite motif-containing protein 72 (TRIM72)

Cat. Num. AAA1451297

• Gene Names: TRIM72; MG53
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Tripartite motif-containing protein 72 (TRIM72); Recombinant Human Tripartite motif-containing protein 72 (TRIM72); TRIM72 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-269aa, full length protein
• Sequence: MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDREAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIIS
• Sequence Length: 269

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 270265876
• NCBI GeneID: 493829
• NCBI Accession #: NP_001008275.2
• NCBI GenBank Nucleotide #: NM_001008274.3
• UniProt Accession #: Q6ZMU5; Q8N4X6; Q8NBD9
• Molecular Weight: 32.5 kDa
• NCBI Official Full Name: tripartite motif-containing protein 72
• NCBI Official Synonym Full Names: tripartite motif containing 72
• NCBI Official Symbol: TRIM72
• NCBI Official Synonym Symbols: MG53
• NCBI Protein Information: tripartite motif-containing protein 72
• UniProt Protein Name: Tripartite motif-containing protein 72
• Protein Family: Tripartite motif-containing protein
• UniProt Gene Name: TRIM72
• UniProt Synonym Gene Names: Mg53

Uniprot Description

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca2+-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles ().