Triggering Receptor Expressed On Myeloid Cells 1 Recombinant Protein | TREM1 recombinant protein

Recombinant Triggering Receptor Expressed On Myeloid Cells 1 (TREM1)

Cat. Num. AAA2031623

• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: Triggering Receptor Expressed On Myeloid Cells 1; Recombinant Triggering Receptor Expressed On Myeloid Cells 1 (TREM1); TREM1 recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Concentration: 8.7 (varies by lot)
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSG SEF- QA ATELPEEKYI LAEGETLNVN CPVTVGVYSN SRKAWQKLNR NGKFQTLAIT ERVSGQVSKV QVGKIFLTDE PSEGMLHVQM TNVQAEDSGL YRCVIYQPPK DPIILFYPVR LVVTNYSSGT PASAETPTQS CSPTTTLPPT TTTNRHRPRP RTVRTVTQFLTDFTTSLSSP GLKVTLTNVT DITRDTEISL ILPAVCGLLS KSLVFIVLFV VTRMSFTP
• Sequence Length: 230

• Applicable Applications for TREM1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 25.8kDa
• Accurate Molecular Mass (KD): 21kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: N-terminal His-Tag
• Organism Species: Sus scrofa; Porcine (Pig)
• Fragment: Gln19~Pro238
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 10946760
• NCBI GeneID: 58217
• NCBI Accession #: NP_067381.1
• NCBI GenBank Nucleotide #: NM_021406.5
• Molecular Weight: 25,409 Da
• NCBI Official Full Name: triggering receptor expressed on myeloid cells 1
• NCBI Official Synonym Full Names: triggering receptor expressed on myeloid cells 1
• NCBI Official Symbol: Trem1
• NCBI Protein Information: triggering receptor expressed on myeloid cells 1
• UniProt Protein Name: Triggering receptor expressed on myeloid cells 1
• Protein Family: Triggering receptor expressed on myeloid cells
• UniProt Gene Name: Trem1
• UniProt Synonym Gene Names: TREM-1
• UniProt Entry Name: TREM1_MOUSE

Uniprot Description

TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; cell; integral to membrane

Biological Process: neutrophil chemotaxis; cell migration; cytokine metabolic process; cytokine secretion during immune response; chemokine metabolic process