SDS-Page
(Figure 1. Human CD30 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
CD30 Ligand Recombinant Protein | CD30 recombinant protein
Recombinant human CD30 Ligand Protein with N-mouse Fc and C-6xHis tag
Shipping: Blue Ice
SDS-Page
(Figure 1. Human CD30 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
SDS-Page
(Figure 1. Human CD30 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
ELISA (EIA)
(Figure 2. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human CD30, His tagged protein can bind Human CD30 Ligand,mFc-His tagged protein in a linear range of 2.56-320 ng/ml.)
ELISA (EIA)
(Figure 2. ELISA plate pre-coated by 2 ug/ml (100 ul/well) Human CD30, His tagged protein can bind Human CD30 Ligand,mFc-His tagged protein in a linear range of 2.56-320 ng/ml.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Uniprot Description
TNFSF8: Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells. Belongs to the tumor necrosis factor family.
Protein type: Apoptosis; Cytokine; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q33
Cellular Component: extracellular space; integral to plasma membrane
Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding
Biological Process: cell proliferation; CD8-positive, alpha-beta T cell differentiation; defense response to Gram-positive bacterium; cell-cell signaling; apoptosis; immune response; positive regulation of transcription from RNA polymerase II promoter; signal transduction
Research Articles on CD30
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Product Notes
The CD30 tnfsf8 (Catalog #AAA188095) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD30 Ligand can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CD30 tnfsf8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: mFc(Pro99- Lys330)+CD 30 Ligand(Gln 63-Asp234). It is sometimes possible for the material contained within the vial of "CD30 Ligand, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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