Rat Osteoprotegerin ELISA Kit | TNFRSF11B elisa kit
Rat Osteoprotegerin (OPG) ELISA Kit
Gene Names
Tnfrsf11b; Opg
Reactivity
Rat
Synonyms
Osteoprotegerin; Rat Osteoprotegerin (OPG) ELISA Kit; MGC29565; OCIF; OPG; TR1; osteoclastogenesis inhibitory factor|osteoprotegerin; TNFRSF11B elisa kit
Reactivity
Rat
Specificity
This assay has high sensitivity and excellent specificity for detection of Rat TNFRSF11B. No significant cross-reactivity or interference between Rat TNFRSF11B and analogues was observed.
Sequence Length
401
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for TNFRSF11B elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate TNFRSF11B in samples. An antibody specific for TNFRSF11B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTNFRSF11B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFRSF11B is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFRSF11B bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,192 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 11B
NCBI Official Synonym Full Names
TNF receptor superfamily member 11B
NCBI Official Symbol
Tnfrsf11b
NCBI Official Synonym Symbols
Opg
NCBI Protein Information
tumor necrosis factor receptor superfamily member 11B
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 11B
Protein Family
UniProt Gene Name
Tnfrsf11b
UniProt Synonym Gene Names
Opg
NCBI Description
plays a role in the negative regulation of bone resorption by inhibiting formation of osteoclasts [RGD, Feb 2006]
Uniprot Description
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis ().
Research Articles on TNFRSF11B
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Product Notes
The Rat TNFRSF11B tnfrsf11b (Catalog #AAA283790) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA283790 ELISA Kit recognizes Rat TNFRSF11B. It is sometimes possible for the material contained within the vial of "Osteoprotegerin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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