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Treponema pallidum TmpA Recombinant Protein | TP0768 recombinant protein

Treponema pallidum TmpA, Recombinant (Syphilis)

Purity
Highly Purified
90% by 10% PAGE (coomassie staining)
Synonyms
Treponema pallidum TmpA; Recombinant (Syphilis); TP0768 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Specificity
Immunoreactive with sera of Trp. Pallidum infected individuals.
Purity/Purification
Highly Purified
90% by 10% PAGE (coomassie staining)
Form/Format
Supplied as a liquid in 10mM Tris-HCl, pH 8.0, 1mM EDTA, 1mM DTT, 8M urea.
Application Notes
Antigen in ELISA and Western Blot, excellent antigen for detection of Trp. Pallidum with minimal specificity problems.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for TP0768 recombinant protein
Treponema pallidum is the causative agent of syphilis. It is a spirochete, a helical to sinusoidal bacterium with outer and cytoplasmic membranes, a thin peptidoglycan layer, and periplasmic flagella. Mechanisms of T. pallidum pathogenesis are poorly understood. No known virulence factors have been identified, and the outer membrane is mostly lipid with a paucity of proteins. Consequently, existing tests for syphilus are suboptimal, and no vaccine against T. pallidum is available. TIGR sequenced the genome of T. pallidum subsp. pallidum (strain Nichols) by the whole genome random sequencing method. The T. pallidum genome is a circular chromosome of 1,138,006 base pairs containing a total of 1041 predicted open reading frames.

The protein contains the Trp. Pallidum Membrane Protein A immunodominant regions.
Product Categories/Family for TP0768 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
37,285 Da
NCBI Official Full Name
Treponemal membrane protein A
NCBI Official Symbol
TP0768
NCBI Protein Information
membrane protein (tmpA)
UniProt Protein Name
Treponemal membrane protein A
UniProt Gene Name
tmpA
UniProt Entry Name
TMPA_TREPA

Uniprot Description

Subcellular location: Cell membrane; Lipid-anchor.

Sequence similarities: To T.phagedenis TmpA.

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Product Notes

The TP0768 tmpa (Catalog #AAA637793) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Antigen in ELISA and Western Blot, excellent antigen for detection of Trp. Pallidum with minimal specificity problems. Researchers should empirically determine the suitability of the TP0768 tmpa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Treponema pallidum TmpA, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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