Western Blot (WB)
(ST8SIA6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ST8SIA6 antibody detected the ST8SIA6 protein (arrow).)
Rabbit anti-Human ST8SIA6 Polyclonal Antibody | anti-ST8SIA6 antibody
ST8SIA6 Antibody (Center)
Western Blot (WB)
(ST8SIA6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ST8SIA6 antibody detected the ST8SIA6 protein (arrow).)
Western Blot (WB)
(ST8SIA6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the ST8SIA6 antibody detected the ST8SIA6 protein (arrow).)
structures involved in cell-cell communication, cell-substrate
interaction, adhesion, and protein targeting. ST8SIA6 belongs to a
family of sialyltransferases (EC 2.4.99.8) that synthesize
sialylglycoconjugates (Takashima et al., 2002 [PubMed
11980897]).
Avril, T., et al. J. Leukoc. Biol. 80(4):787-796(2006)
Harduin-Lepers, A., et al. Glycobiology 15(8):805-817(2005)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Takashima, S., et al. J. Biol. Chem. 277(27):24030-24038(2002)
NCBI and Uniprot Product Information
NCBI Description
Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).[supplied by OMIM, Mar 2008]
Uniprot Description
ST8SIA6: Prefers O-glycans to N-glycans or glycolipids as acceptor substrates. The minimal acceptor substrate is the NeuAc- alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups. Belongs to the glycosyltransferase 29 family.
Protein type: Membrane protein, integral; EC 2.4.99.-; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Transferase
Chromosomal Location of Human Ortholog: 10p12.33
Cellular Component: Golgi membrane; integral to Golgi membrane
Molecular Function: sialyltransferase activity
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; glycoprotein metabolic process; glycolipid biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; carbohydrate biosynthetic process; oligosaccharide metabolic process; ganglioside biosynthetic process
Research Articles on ST8SIA6
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Product Notes
The ST8SIA6 st8sia6 (Catalog #AAA9206387) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ST8SIA6 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ST8SIA6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ST8SIA6 st8sia6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST8SIA6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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