Transferrin receptor protein 1 (Tfrc) Recombinant Protein | Tfrc recombinant protein
Recombinant Rat Transferrin receptor protein 1 (Tfrc)
Gene Names
Tfrc; Trfr
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Transferrin receptor protein 1 (Tfrc); Recombinant Rat Transferrin receptor protein 1 (Tfrc); Tfrc recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-622, full length protein
Sequence
IEFTDIIKQLSQNTYTPREAGSQKDENLAYYIENLFHDFKFSKVWRDEHYVKIQVKNSVSQNLVTINSGSNIDPVEAPEGYVAFSKAGEVTGKLVHANFGTKKDFEELNYSVNGSLVIVRAGKITFAEKVANAQSFNAIGVLIYMDRNTFPVVEADLQFFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPSIPVQTISRAPAEKLFKNMEGNCPPSWNIDSSCKLELSQNQNVKLTVNNVLKETRILNIFGVIKGYEEPDRYIVVGAQRDAWGPGVAKSSVGTGLLLKLAQVFSDMISKDGFRPSRSIIFASWTAGDYGAVGPTEWLEGYLSSLHLKAFTYINLDKVVLGTSNFKVSASPLLYTLMGKIMQDVKHPIDGKYLYRNSNWISKIEELSLDNAAFPFLAYSGIPAVSFCFCEDEDYPYLGTKLDTYEILIQKVPQLNQMVRTAAEVAGQFIIKLTHDIELTLDYEMYNSKLLSFMKDLNQFKADIKDMGLSLQWLYSARGDYFRATSRLTTDFHNAEKTNRFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVENLRLRQKNITAFNETLFRNQLALATWTIQGVANALSGDIWNIDNEF
Sequence Length
622
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
70,153 Da
NCBI Official Full Name
Transferrin receptor protein 1
NCBI Official Synonym Full Names
transferrin receptor
NCBI Official Symbol
Tfrc
NCBI Official Synonym Symbols
Trfr
NCBI Protein Information
transferrin receptor protein 1
UniProt Protein Name
Transferrin receptor protein 1
Protein Family
UniProt Gene Name
Tfrc
UniProt Synonym Gene Names
Trfr; TR; TfR; TfR1; Trfr
NCBI Description
receptor for transferrin; involved in regulating stellate cell activation [RGD, Feb 2006]
Uniprot Description
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (). Positively regulates T and B cell proliferation through iron uptake ().
Research Articles on Tfrc
Similar Products
Product Notes
The Tfrc tfrc (Catalog #AAA1331677) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-622, full length protein. The amino acid sequence is listed below: IEFTDIIKQL SQNTYTPREA GSQKDENLAY YIENLFHDFK FSKVWRDEHY VKIQVKNSVS QNLVTINSGS NIDPVEAPEG YVAFSKAGEV TGKLVHANFG TKKDFEELNY SVNGSLVIVR AGKITFAEKV ANAQSFNAIG VLIYMDRNTF PVVEADLQFF GHAHLGTGDP YTPGFPSFNH TQFPPSQSSG LPSIPVQTIS RAPAEKLFKN MEGNCPPSWN IDSSCKLELS QNQNVKLTVN NVLKETRILN IFGVIKGYEE PDRYIVVGAQ RDAWGPGVAK SSVGTGLLLK LAQVFSDMIS KDGFRPSRSI IFASWTAGDY GAVGPTEWLE GYLSSLHLKA FTYINLDKVV LGTSNFKVSA SPLLYTLMGK IMQDVKHPID GKYLYRNSNW ISKIEELSLD NAAFPFLAYS GIPAVSFCFC EDEDYPYLGT KLDTYEILIQ KVPQLNQMVR TAAEVAGQFI IKLTHDIELT LDYEMYNSKL LSFMKDLNQF KADIKDMGLS LQWLYSARGD YFRATSRLTT DFHNAEKTNR FVMREINDRI MKVEYHFLSP YVSPRESPFR HIFWGSGSHT LSALVENLRL RQKNITAFNE TLFRNQLALA TWTIQGVANA LSGDIWNIDN EF. It is sometimes possible for the material contained within the vial of "Transferrin receptor protein 1 (Tfrc), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
