Transcobalamin-2 (TCN2) Recombinant Protein | TCN2 recombinant protein
Recombinant Human Transcobalamin-2 (TCN2)
Gene Names
TCN2; II; TC; TC2; TC-2; TCII; TC II; D22S676; D22S750
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Transcobalamin-2 (TCN2); Recombinant Human Transcobalamin-2 (TCN2); TCN2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
19-427, Full length protein
Sequence
EMCEIPEMDSHLVEKLGQHLLPWMDRLSLEHLNPSIYVGLRLSSLQAGTKEDLYLHSLKLGYQQCLLGSAFSEDDGDCQGKPSMGQLALYLLALRANCEFVRGHKGDRLVSQLKWFLEDEKRAIGHDHKGHPHTSYYQYGLGILALCLHQKRVHDSVVDKLLYAVEPFHQGHHSVDTAAMAGLAFTCLKRSNFNPGRRQRITMAIRTVREEILKAQTPEGHFGNVYSTPLALQFLMTSPMRGAELGTACLKARVALLASLQDGAFQNALMISQLLPVLNHKTYIDLIFPDCLAPRVMLEPAAETIPQTQEIISVTLQVLSLLPPYRQSISVLAGSTVEDVLKKAHELGGFTYETQASLSGPYLTSVMGKAAGEREFWQLLRDPNTPLLQGIADYRPKDGETIELRLVSW
Sequence Length
409
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for TCN2 recombinant protein
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,421 Da
NCBI Official Full Name
transcobalamin-2 isoform 1
NCBI Official Synonym Full Names
transcobalamin 2
NCBI Official Symbol
TCN2
NCBI Official Synonym Symbols
II; TC; TC2; TC-2; TCII; TC II; D22S676; D22S750
NCBI Protein Information
transcobalamin-2
UniProt Protein Name
Transcobalamin-2
Protein Family
UniProt Gene Name
TCN2
UniProt Synonym Gene Names
TC2; TC-2; TC II; TCII
NCBI Description
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Uniprot Description
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.
Research Articles on TCN2
Similar Products
Product Notes
The TCN2 tcn2 (Catalog #AAA966735) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-427, Full length protein. The amino acid sequence is listed below: EMCEIPEMDS HLVEKLGQHL LPWMDRLSLE HLNPSIYVGL RLSSLQAGTK EDLYLHSLKL GYQQCLLGSA FSEDDGDCQG KPSMGQLALY LLALRANCEF VRGHKGDRLV SQLKWFLEDE KRAIGHDHKG HPHTSYYQYG LGILALCLHQ KRVHDSVVDK LLYAVEPFHQ GHHSVDTAAM AGLAFTCLKR SNFNPGRRQR ITMAIRTVRE EILKAQTPEG HFGNVYSTPL ALQFLMTSPM RGAELGTACL KARVALLASL QDGAFQNALM ISQLLPVLNH KTYIDLIFPD CLAPRVMLEP AAETIPQTQE IISVTLQVLS LLPPYRQSIS VLAGSTVEDV LKKAHELGGF TYETQASLSG PYLTSVMGKA AGEREFWQLL RDPNTPLLQG IADYRPKDGE TIELRLVSW. It is sometimes possible for the material contained within the vial of "Transcobalamin-2 (TCN2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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